Effect of différente gonadotrophins on the follicular development and ovulation in guinea pig (Cavia porcellus)

Authors

  • Jefferson Aparecido Guilén Soares Universidade Estadual de Londrina, Centro de Ciências Agrárias, Londrina, PR
  • Valquiria Hvppólito Barnabe Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • José Antonio Visintin Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • Edwiges Maristela Fituco Instituto Biológico de São Paulo, São Paulo, SP
  • Renato Campanarut Barnabe Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • leda Terezinha Nascimento Verreschi Escola Paulista de Medicina, São Paulo, SP

DOI:

https://doi.org/10.11606/issn.2318-3659.v33i2p110-114

Keywords:

Ovulation, Superovulation, Gonadotrophins, Guinea pig.

Abstract

Superovulatory response in guinea pigs submitted to various gonadotrophins was studied in 60 females, equally divided in 10 groups with 6 animals each. In a first phase, each one of 6 groups received PMSG, FSH-p in a single dosis, FSH-p in 3 doses, FSH-h, HMG and NaCI 0.9% (control group), respectively. In a second phase, 4 groups received each one, 22 IU FSH-h, 15 IU FSH-h, HMG and NaCI 0.9% (control group), respectively. Three experimental groups of 2nd. phase also received PGF2alfa. Except for the 2 controls, all groups also received HCG. The 3 first groups of 1st phase presented blocked ovulation. The PMSG-treated group showed generalized luteinization of the ovaries, and the others had
early folicular luteinization with entrapment of ova. In 2nd phase, a group showed an average number of ovulations - considered as normal for the species - and 2 animals had superovulations. It may be concluded that PGF2alfa takes part in the ovulation mechanism of guinea pigs and that it is possible to increase multiple follicular development by using FSH-h + HCG and HMG + HCG associated or not with PGF2alfa.

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Published

1996-06-01

How to Cite

Soares, J. A. G., Barnabe, V. H., Visintin, J. A., Fituco, E. M., Barnabe, R. C., & Verreschi, leda T. N. (1996). Effect of différente gonadotrophins on the follicular development and ovulation in guinea pig (Cavia porcellus). Brazilian Journal of Veterinary Research and Animal Science, 33(2), 110-114. https://doi.org/10.11606/issn.2318-3659.v33i2p110-114

Issue

Section

ANIMAL REPRODUCTION

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