Comparative study between the effects of gelatin-resorcin-formaldehyde (Colagel®) and n-butil-2-cianoacrilate (Histoacryl®) in rabbit cervical esophagotony
Keywords:Adhesives, Cyanoacrylate, Rabbits, Hsophagoplasty, Gelalin-Resorcin and formaldehyde
AbstractThe objetive of the study was to test two types of adhesives, Colager and HistoacryP in the impermeabilization of the suture line, by comparing them to classic esophagotomy, because of the anatomic peculiarity of the esophagous in relation to dehiscence, mostly in humans.The experiment was conducted in 12 rabbits, and the clinic, macroscopic and microscopic patterns of the wounds were observed in three different times, which are related to distinct phases of the healing process.The results show an intense infiltrate of polymorphonuclear cells (mainly eosinophils) in animals in which it was utilized the Colager, compared to controls and to the animals in which it was used the Histoacryl®. Based on these results it was infered that the healing process was delayed in injuries in which Colager was applied.
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