Effects of amitraz on isolation-induced aggression in mice
Keywords:Amitraz, Aggressive behavior, Social isolation, Serotonin, Catecholamines, Mice
The effects of amitraz, a formamidine derivative on isolation-induced aggression were studied in mice. Results show that amitraz increased the latency to the first attack and increased not only the fight duration but also the frequencies of attacks and tail flickings. These results suggested that pesticide effects on aggressive behavior could be a consequence of it’s inhibitory effects on monoamine oxidase activity within the Central Nervous System, most probably through the increments it produces on serotonin levels.
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