Effects of amitraz on isolation-induced aggression in mice

Authors

  • Michiko Sakate Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Botucatu, SP
  • Jorge Camilo Flório Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • João Palermo Neto Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.1993.52011

Keywords:

Amitraz, Aggressive behavior, Social isolation, Serotonin, Catecholamines, Mice

Abstract

The effects of amitraz, a formamidine derivative on isolation-induced aggression were studied in mice. Results show that amitraz increased the latency to the first attack and increased not only the fight duration but also the frequencies of attacks and tail flickings. These results suggested that pesticide effects on aggressive behavior could be a consequence of it’s inhibitory effects on monoamine oxidase activity within the Central Nervous System, most probably through the increments it produces on serotonin levels.

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Published

1993-06-01

Issue

Section

BASIC SCIENCES

How to Cite

1.
Sakate M, Flório JC, Palermo Neto J. Effects of amitraz on isolation-induced aggression in mice. Braz. J. Vet. Res. Anim. Sci. [Internet]. 1993 Jun. 1 [cited 2024 Apr. 19];30(1):17-9. Available from: https://www.revistas.usp.br/bjvras/article/view/52011