Genetic characterization of bovine viral diarrhoea virus detected in persistently infected cattle in Southern Minas Gerais, Brazil

Authors

  • Fabio Carvalho Dias Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Departamento de Medicina Veterinária Preventiva e Reprodução Animal, Jaboticabal, SP
  • Kerlei Cristina Médici Universidade Estadual de Londrina, Departamento de Medicina Veterinária Preventiva, Laboratório de Virologia Animal, Londrina, PA
  • Ricardo Luiz Moro de Sousa Universidade de São Paulo, Faculdade de Zootecnia e Engenharia de Alimentos, Departamento de Ciências Básicas, Pirassununga, SP
  • Amauri Alcindo Alfieri Universidade Estadual de Londrina, Departamento de Medicina Veterinária Preventiva, Laboratório de Virologia Animal, Londrina, PA
  • Samir Issa Samara Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Departamento de Medicina Veterinária Preventiva e Reprodução Animal, Jaboticabal, SP

DOI:

https://doi.org/10.11606/issn.1678-4456.v49i6p452-458

Keywords:

Bovine viral diarrhoea virus, Persistently infected animal, Genotypic characterization, Brazil

Abstract

Isolates of bovine viral diarrhoea virus (BVDV) detected in serum samples of two persistently infected animals (PI) identified in a herd located in the southern state of Minas Gerais, Brazil, underwent genetic characterization trough partial nucleotide sequencing and analysis of the 5’ Untranslated Region (5’UTR) of the viral genome. The isolates were characterized as belonging to genotype BVDV-1, subgenotype BVDV-1b. The results of this study suggest BVDV-1b as an agent of importance in the occurrence of bovine viral diarrhoea (BVD) in the herds of the region. Moreover, the genotypic characterization of isolates of BVDV helps to better understand the epidemiology of the disease, as the genetic variability of BVDV interferes in the serological tests and has implications for the use of vaccines, whose majority is produced only with reference strains of BVDV. Therefore, the investigation on the genetic diversity of BVDV existing in Brazil is required for the improvement of the disease prevention and control measures

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Published

2012-12-11

Issue

Section

UNDEFINIED

How to Cite

1.
Dias FC, Médici KC, Sousa RLM de, Alfieri AA, Samara SI. Genetic characterization of bovine viral diarrhoea virus detected in persistently infected cattle in Southern Minas Gerais, Brazil. Braz. J. Vet. Res. Anim. Sci. [Internet]. 2012 Dec. 11 [cited 2024 Jul. 19];49(6):452-8. Available from: https://www.revistas.usp.br/bjvras/article/view/53921