Compared study on the effects of mechanical controled ventilation (MCV) with or without the use of positive-end-expiratory-pressure (PEEP) on inter-pleural pressure variation in horse anesthesia

Authors

  • Melaine Klemm Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia, São Paulo, SP
  • José Alvarenga Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia, São Paulo, SP
  • Denise Tabacchi Fantoni Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia, São Paulo, SP
  • Luis Cláudio Lopes Correia Silva Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia, São Paulo, SP
  • José Otávio Auler Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia, São Paulo, SP

DOI:

https://doi.org/10.1590/S1413-95961998000600006

Keywords:

Anesthesia, Artificial respiration, Equine

Abstract

One of the main death causes in equines during anesthesia and recovery periods is hipoxemia due to intrapulmonary "shunts". In human beings, hipoxy is treated with the use of Positive-End- Expiratory Pressure (PEEP), that in this species hinders airway closure, increases functional residual capacity and improves arterial oxygenation. We studied the effects of PEEP on inter-pleural pressure and on the cardio-vascular system, comparing Spontaneous Ventilation (SV), with Controlled Mechanical Ventilation (CMV) by itself and with PEEP of 10 cm H2O. We used 12 adult horses, females and males. These animals were submitted to general anesthesia with SV, CMV and CMV with PEEP of 10 cm H2O. The anesthetic procedure was equal for all horses. The hemodynamic, ventilatory and oxygenation parameters were evaluated. The statistical analysis of the results showed that when comparing SV, CMV and CMV with PEEP, there was no significant decrease in arterial blood pressure, nor significant alterations in cardiac and respiratory rate, pH, HCO3, BE and SatHb. When comparing SV, and CMV, an increase in PaO2 was noticed, parallel to a constant increase in PaCO2. No significant alterations in "shunt", alveolar-arterial relation and oxygen contend, were noticed. However during CMV and CMV with PEEP lower "shunt" values were noticed. Inter-pleural pressure showed significant alterations, decreasing during CMV and with CMV with PEEP, in comparison to VE. We concluded that CMV and CMV with PEEP of 10 cm H2O do not harm the cardio-respiratory system.

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Published

1998-01-01

How to Cite

Klemm, M., Alvarenga, J., Fantoni, D. T., Silva, L. C. L. C., & Auler, J. O. (1998). Compared study on the effects of mechanical controled ventilation (MCV) with or without the use of positive-end-expiratory-pressure (PEEP) on inter-pleural pressure variation in horse anesthesia. Brazilian Journal of Veterinary Research and Animal Science, 35(6), 260-265. https://doi.org/10.1590/S1413-95961998000600006

Issue

Section

VETERINARY MEDICINE

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