Hematological and biochemical profiles of rats (Rattus norvegicus) kept under microenvironmental ventilation system
Keywords:Laboratory animals, Rats, Hematology, Biochemistry, Ventilation
AbstractPrevious studies reported that rats (Rattus norvegicus) kept under microenvironmental ventilation systems (MEV) present better productive and health parameters when compared to animals kept under general diluting ventilation (GDV). The objective of the present research trial was to evaluate hematological and biochemical profiles of rats kept under MVS. In order to achieve this objective, two different trials were designed: Trail 1 (E1), in which it was evaluated the reproductive performance of males and females submitted to two different air speed limits - FV1, from 0.03 to 0.26 m / sec and FV2, from 0.27 to 0.80 m / sec. In Trial 2 (E2) it was evaluated different bed change intervals (3, 5, 7 and 9 days), for males kept under constant air speed (0.5 m / sec). Values for hemogram and biochemical patterns of these animals were compared to those of rats kept under GDV. Results show statistical differences in some of the studied parameters not only for the comparison between GVD and E1 and GVD and E2, but also between both groups submitted to MEV (E1 and E2). However, values found for all studied parameters are inside the normal range reported for this species, what indicates that MEV does not induce important changes in the physiological parameters evaluated.
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Teixeira, M. A., Chaguri, L. do C. A. G., Carissimi, A. S., Souza, N. L. de, Mori, C. M. C., Gomes, V. M. W., Poli Neto, A., Nonoyama, K., & Merusse, J. L. B. (2000). Hematological and biochemical profiles of rats (Rattus norvegicus) kept under microenvironmental ventilation system. Brazilian Journal of Veterinary Research and Animal Science, 37(5), 342-347. https://doi.org/10.1590/S1413-95962000000500001
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