Phytochemical evaluation and wound healing potential of the fruit extract ethanolic of Jucá (Libidibia ferrea) in Wistar rats

Authors

  • Yuri Teiichi da Silva Kobayashi Universidade Federal do Pará
  • Vívian Tavares de Almeida Universidade Federal do Pará
  • Talita Bandeira Universidade Federal do Pará
  • Bianca Nascimento de Alcântara Universidade Federal do Pará
  • Andressa Santa Brígida da Silva Universidade Federal do Pará
  • Wagner Luiz Ramos Barbosa Universidade Federal do Pará
  • Paula Barbosa da Silva Universidade Federal do Pará
  • Maria Vivina Barros Monteiro Universidade Federal do Pará
  • Milton Begeres de Almeida Universidade Federal do Pará

DOI:

https://doi.org/10.11606/issn.1678-4456.v52i1p34-40

Keywords:

Skin, Healing, Plant drug

Abstract

Libidibia ferrea is a plant popularly used for therapeutic purposes, including processes to accelerate wound healing. The present investigation analyzed the chemical composition and the healing potential of ethanolic extract of the fruits of L. ferrea (Mart. ex Tul.) in rats. This study used 24 Wistar rats divided into four groups. In all animals a piece of skin on the back was removed and each group received a different treatment: NaCl 0.9%, Chlorhexidine digluconate 1%, ethanol extract of the fruits of Libidibia ferrea 12.5% and 50%. The healing process was evaluated macroscopically and microscopically. The ethanolic extract of the fruits of L. ferrea 12.5% was significantly more efficient than the 50% healing in rat skin.

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Published

2015-04-13

Issue

Vol. 52 No. 1 (2015)

Section

ARTICLES

License

The journal content is authorized under the Creative Commons  BY-NC-SA  license (summary of the license: https://creativecommons.org/licenses/by-nc-sa/4.0 | full text of the license: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode) 

How to Cite

1.
Kobayashi YT da S, Almeida VT de, Bandeira T, Alcântara BN de, Silva ASB da, Barbosa WLR, et al. Phytochemical evaluation and wound healing potential of the fruit extract ethanolic of Jucá (Libidibia ferrea) in Wistar rats. Braz. J. Vet. Res. Anim. Sci. [Internet]. 2015 Apr. 13 [cited 2024 Apr. 19];52(1):34-40. Available from: https://www.revistas.usp.br/bjvras/article/view/61477