Syzygium cumini and the regeneration of insulin positive cells from the pancreatic duct

Authors

  • Deila Rosély C. Schossler Universidade Federal de Santa Maria, Departamento de Morfologia, Santa Maria, RS
  • Cinthia Melazzo Mazzanti Universidade Federal do Rio Grande do Sul, Departamento de Bioquímica, Porto Alegre, RS
  • Sônia Cristina Almeida da Luz Universidade Federal de Santa Maria, Departamento de Morfologia, Santa Maria, RS
  • Andreane Filappi Universidade Federal de Santa Maria, Departamento de Medicina de Grandes Animais, Santa Maria, RS
  • Danívia Prestes Universidade Federal de Santa Maria, Departamento de Medicina de Grandes Animais, Santa Maria, RS
  • Aron Ferreira da Silveira Universidade Federal de Santa Maria, Departamento de Morfologia, Santa Maria, RS
  • Marcelo Cecim Universidade Federal de Santa Maria, Departamento de Medicina de Grandes Animais, Santa Maria, RS

DOI:

https://doi.org/10.1590/S1413-95962004000400003

Keywords:

Syzygium cumini, Alloxan, Diabetes, Immunohistochemistry

Abstract

Syzygium cumini is a plant that has been used in popular medicine for the treatment of insulin dependent diabetes mellitus (DMID). This study verified the effect of Syzygium cumini upon the regeneration of insulin producing cells in the pancreatic duct wall. The animals were divided into four groups, control (C), treated control (TC), diabetic control (DC) and treated diabetic (TD). An aqueous extract from Syzygium cumini bark was given by gavage in a daily dose of 1g/kg of body weight. After a thirty day period the animals were euthanized and the pancreas taken to immunohistochemical analysis. In this study, it was observed the positive staining for insulin on cells of the pancreatic duct and connective tissue in the pancreas of TD and TC animals. These results indicate that Syzygium cumini bark extract stimulates development of insulin positive cells from the pancreatic duct epithelial cells.

Downloads

Download data is not yet available.

Downloads

Published

2004-08-01

How to Cite

Schossler, D. R. C., Mazzanti, C. M., Luz, S. C. A. da, Filappi, A., Prestes, D., Silveira, A. F. da, & Cecim, M. (2004). Syzygium cumini and the regeneration of insulin positive cells from the pancreatic duct. Brazilian Journal of Veterinary Research and Animal Science, 41(4), 236-239. https://doi.org/10.1590/S1413-95962004000400003

Issue

Section

UNDEFINIED

Most read articles by the same author(s)