Polycystic ovarian syndrome: temporal characterization of the induction and reversion process in an experimental model

Authors

  • Natalia R. Salvetti National University of Litoral, Faculty of Veterinary Sciences, Center for Experimental Biology and Laboratory Animals
  • Ana M. Canal National University of Litoral, Faculty of Veterinary Sciences, Department of Basic Pathology of the Faculty
  • Eduardo J. Gimeno National University of La Plata, Faculty of Veterinary Sciences, Institute of Pathology
  • Hugo H. Ortega National University of Litoral, Faculty of Veterinary Sciences, Center for Experimental Biology and Laboratory Animals

DOI:

https://doi.org/10.1590/S1413-95962004000600006

Keywords:

Histopathology, Ovary, PCOD, Polycystic ovarian syndrome, Rat

Abstract

Numerous experimental models have been developed for the study of the polycystic ovarian syndrome in the rat. In the present study, the syndrome was induced by exposure to constant light. The process was evaluated during its induction and also during its reversion. The estral cycle was analyzed through the vaginal cytology; reproductive parameters were evaluated by mating, as well as the ovarian morphology. All the animals developed the syndrome after 13 weeks of permanent light. The histologic characteristics of the ovaries, at week 15, were similar to those observed in the polycystic ovarian syndrome in human and other species. After regression of the syndrome, there was not difference in any of the evaluated reproductive parameters, when compared with the control group.

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Published

2004-11-01

How to Cite

Salvetti, N. R., Canal, A. M., Gimeno, E. J., & Ortega, H. H. (2004). Polycystic ovarian syndrome: temporal characterization of the induction and reversion process in an experimental model. Brazilian Journal of Veterinary Research and Animal Science, 41(6), 389-395. https://doi.org/10.1590/S1413-95962004000600006

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