Anti-arthritic potential of the plant Justicia gendarussa Burm F

Authors

  • Jaijesh Paval Melaka Manipal Medical College; Department of Anatomy
  • Srinivasan Keloth Kaitheri Manipal College of Pharmaceutical Science; Department of Pharmaceutical Chemistry
  • Bhagath Kumar Potu Kasturba Medical College; Department of Anatomy
  • Sreejith Govindan Melaka Manipal Medical College; Department of Microbiology
  • Raju Suresh Kumar Melaka Manipal Medical College; Department of Physiology
  • Sareesh Naduvil Narayanan Melaka Manipal Medical College; Department of Physiology
  • Sudheer Moorkoth Manipal College of Pharmaceutical Science; Department of Pharmaceutical Chemistry

DOI:

https://doi.org/10.1590/S1807-59322009000400015

Keywords:

Arthritis, Plant extract, Aspirin, Collagen, Rat

Abstract

OBJECTIVE: To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models. MATERIALS AND METHOD: The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin. RESULTS: The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential.

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Published

2009-04-01

Issue

Vol. 64 No. 4 (2009)

Section

Basic Research

How to Cite

Anti-arthritic potential of the plant Justicia gendarussa Burm F . (2009). Clinics, 64(4), 357-362. https://doi.org/10.1590/S1807-59322009000400015