Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype

Authors

  • Giselle Izzo Universidade de São Paulo; Faculdade de Medicina; Department and Institute of Psychiatry; Laboratory of Neuroscience
  • Orestes V. Forlenza Universidade São Paulo; Center for Interdisciplinary Research on Applied Neurosciences
  • Bernardo dos Santos Universidade de São Paulo; Instituto de Matemática e Estatística
  • Paulo H. F. Bertolucci Federal University of Saio Paulo; Faculty of Medicine; Department of Neurology; Nucleo De Envelhecimento Cerebral
  • Elida B. Ojopi Universidade de São Paulo; Faculdade de Medicina; Department and Institute of Psychiatry; Laboratory of Neuroscience
  • Wagner F. Gattaz Universidade São Paulo; Center for Interdisciplinary Research on Applied Neurosciences
  • Daniel Shikanai Kerr Universidade São Paulo; Center for Interdisciplinary Research on Applied Neurosciences

DOI:

https://doi.org/10.6061/CLINICS/2013(02)RC01

Abstract

In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele.

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Published

2013-01-01

Issue

Vol. 68 No. 2 (2013)

Section

Rapid Communication

How to Cite

Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer’s disease: interactions with the APOE genotype . (2013). Clinics, 68(2), 277-280. https://doi.org/10.6061/CLINICS/2013(02)RC01