Dentinogenesis imperfecta type II: a case report
Keywords:Dentinogenesis imperfecta, Diagnosis, Case report
Objective: Dentinogenesis imperfecta (DI) type II is a rare dentin development disorder with an autosomal dominant inheritance that affects both functional and aesthetic aspects of deciduous and permanent dentitions. This study reports the clinical case of a patient diagnosed late with this anomaly. Material and methods: Male patient, 33 years old, sought dental care complaining of dental aesthetic dissatisfaction. During clinical examination, it was observed that the teeth had a brownish color, with wear and tear of the dental enamel and dentin exposure. Radiographically, the teeth presented the pulp chambers and root canals obliterated, in addition to bulbous crowns. The patient reported that several members of his family had the same condition. The established clinical diagnosis was DI type II. Conclusion: In this case, type II dentinogenesis imperfecta was diagnosed late and without adequate therapeutic intervention, causing aesthetic and functional damage to the patient.
de La Dure-Molla M, Fournier BP, Berdal A. Isolated dentinogenesis imperfecta and dentin dysplasia: revision of the classification. Eur J Hum Genet. 2015; 23(4):445-51. doi: http://doi.org/10.1038/ejhg.2014.159.
Li F, Liu Y, Liu H, Yang J, Zhang F, Feng H. Phenotype and genotype analyses in seven families with dentinogenesis imperfect or dentin dysplasia. Oral Dis. 2016;23(3):360-6. doi: http://doi.org/10.1111/odi.12621.
Andersson K, Malmgren B, Aström E, Dahllöf G. Dentinogenesis imperfecta type II in Swedsih children and adolescents. Orphanet J Rare Dis. 2018;13(1):145. doi: http://doi.org/10.1186/s13023-018-0887-2.
Gama FJR, Corrêa IS, Valério CS, Ferreira EF, Manzi FR. Dentinogenesis imperfecta type II: a case report with 17 years of follow-up. Imaging Sci Dent. 2017;47(2):129-33. doi: http://doi.org/10.5624/isd.2017.47.2.129.
Shields ED, Bixler D, El-Kafrawy AM. A proposed classification for heritable human dentin defects with a description of a new entity. Arch Oral Biol. 1973;18(4):543-53. doi: http://doi.org/10.1016/0003-9969(73)90075-7.
Acevedo AC, Santos LJS, Paula LM, Dong J, MacDougall M. Phenotype characterization and DSPP mutational analysis of the three Brazilian dentinogenesis imperfect type II families. Cells Tissues Organs. 2009;189:230-6. doi: http://doi.org/10.1159/000152917.
Soliman S, Meyer-Marcotty P, Hahn B, Halbleib K, Krastl G. Treatment of an adolescent patient with dentinogenesis imperfecta using indirect composite restorations: a case report and literature review. J Adhes Dent. 2018;20(4):345-54. doi: http://doi.org/10.3290/j.jad.a40991.
Goodman DB. Dentinogenesis imperfecta. Int J Orthod. 1973;11(1):11-6.
Kim JW, Simmer JR. Hereditary dentin defects. J Dent Res. 2007;86(5):392-99. doi: http://doi.org/10.1177/154405910708600502.
Dean JA, Hartsfield JK, Wright JT, Hart TC. Dentin dysplasia type II linkage to chromosome 4q. J Craniofac Genet Dev Biol. 1997;17(4):172-7.
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