Cytotoxicity and biocompatibility of direct and indirect pulp capping materials

Authors

  • Karin Cristina da Silva Modena University of São Paulo; Bauru School of Dentistry; Department of Operative Dentistry, Endodontics and Dental Materials
  • Leslie Caroll Casas-Apayco University of São Paulo; Bauru School of Dentistry; Department of Operative Dentistry, Endodontics and Dental Materials
  • Maria Teresa Atta University of São Paulo; Bauru School of Dentistry; Department of Operative Dentistry, Endodontics and Dental Materials
  • Carlos Alberto de Souza Costa State University of São Paulo; Araraquara Dental School; Department of Physiology and Pathology
  • Josimeri Hebling State University of São Paulo; Araraquara Dental School; Department of Orthodontics and Pediatric Dentistry
  • Carla Renata Sipert University of São Paulo; Bauru School of Dentistry; Department of Biological Sciences
  • Maria Fidela de Lima Navarro University of São Paulo; Bauru School of Dentistry; Department of Operative Dentistry, Endodontics and Dental Materials
  • Carlos Ferreira Santos University of São Paulo; Bauru School of Dentistry; Department of Biological Sciences

DOI:

https://doi.org/10.1590/S1678-77572009000600002

Keywords:

Cytotoxicity, Dental pulp capping, Fibroblasts, Odontoblasts

Abstract

There are several studies about the cytotoxic effects of dental materials in contact with the pulp tissue, such as calcium hydroxide (CH), adhesive systems, resin composite and glass ionomer cements. The aim of this review article was to summarize and discuss the cytotoxicity and biocompatibility of materials used for protection of the dentin-pulp complex, some components of resin composites and adhesive systems when placed in direct or indirect contact with the pulp tissue. A large number of dental materials present cytotoxic effects when applied close or directly to the pulp, and the only material that seems to stimulate early pulp repair and dentin hard tissue barrier formation is CH.

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Published

2009-12-01

Issue

Vol. 17 No. 6 (2009)

Section

Review

License

Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.

 

 

How to Cite

Cytotoxicity and biocompatibility of direct and indirect pulp capping materials . (2009). Journal of Applied Oral Science, 17(6), 544-554. https://doi.org/10.1590/S1678-77572009000600002