In vitro adherence of Candida albicans isolated from patients with chronic periodontitis

Authors

  • Adriana Gadotti Machado State University of São Paulo; São José dos Campos Dental School; Department of Biosciences and Oral Diagnosis
  • Edson Yukio Komiyama State University of São Paulo; São José dos Campos Dental School; Department of Biosciences and Oral Diagnosis
  • Silvana Soléo Ferreira dos Santos University of Taubaté; Department of Dentistry
  • Antonio Olavo Cardoso Jorge State University of São Paulo; São José dos Campos Dental School; Department of Biosciences and Oral Diagnosis
  • Fernanda Lourenção Brighenti State University of São Paulo; São José dos Campos Dental School; Department of Biosciences and Oral Diagnosis
  • Cristiane Yumi Koga-Ito State University of São Paulo; São José dos Campos Dental School; Department of Biosciences and Oral Diagnosis

DOI:

https://doi.org/10.1590/S1678-77572011005000014

Keywords:

Candida albicans, Cell adhesion, Periodontitis, Virulence factors

Abstract

Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.

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Published

2011-08-01

Issue

Vol. 19 No. 4 (2011)

Section

Original Articles

License

Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.

 

 

How to Cite

In vitro adherence of Candida albicans isolated from patients with chronic periodontitis . (2011). Journal of Applied Oral Science, 19(4), 384-387. https://doi.org/10.1590/S1678-77572011005000014