In vitro adherence of Candida albicans isolated from patients with chronic periodontitis
DOI:
https://doi.org/10.1590/S1678-77572011005000014Keywords:
Candida albicans, Cell adhesion, Periodontitis, Virulence factorsAbstract
Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.Downloads
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Published
2011-08-01
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Original Articles
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Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.
How to Cite
In vitro adherence of Candida albicans isolated from patients with chronic periodontitis . (2011). Journal of Applied Oral Science, 19(4), 384-387. https://doi.org/10.1590/S1678-77572011005000014