Anticaries effect of dentifrices with calcium citrate and sodium trimetaphosphate

  • Alberto Carlos Botazzo Delbem Univ. Estadual Paulista; Araçatuba Dental School
  • Maurício Bergamaschi Methodist University of Piracicaba; Lins Dental School
  • Eliana Rodrigues State University of Campinas; Piracicaba Dental School,
  • Kikue Takebayashi Sassaki Univ. Estadual Paulista; Araçatuba Dental School
  • Ana Elisa de Mello Vieira Univ. Estadual Paulista; Araçatuba Dental School
  • Emilene Macario Coimbra Missel Univ. Estadual Paulista; Araçatuba Dental School
Keywords: Dentifrices, Dental enamel, Fluorides, Calcium citrate, Tooth demineralization

Abstract

Because of the growing concerns regarding fluoride ingestion by young children and dental fluorosis, it is necessary to develop new dentifrices. OBJECTIVE: The aim of this study was to evaluate the effect of dentifrices with calcium citrate (Cacit) and sodium trimetaphosphate (TMP) on enamel demineralization. MATERIAL AND METHODS: Enamel blocks (n=70), previously selected through surface hardness analysis, were submitted to daily treatment with dentifrices diluted in artificial saliva and to a pH-cycling model. The fluoride concentration in dentifrices was 0, 250, 450, 550, 1,000 and 1,100 µg F/g. CrestTM was used as a positive control (1,100 mg F/g). Cacit (0.25%) and TMP (0.25%) were added to dentifrices with 450 and 1,000 µg F/g. Surface hardness was measured again and integrated loss of subsurface hardness and fluoride concentration in enamel were calculated. Parametric and correlation tests were used to determine difference (p<0.05) and dose-response relationship between treatments. RESULTS: The addition of Cacit and TMP did not provide a higher fluoride concentration in enamel, however it reduced (p<0.05) mineral loss when compared to other dentifrices; the dentifrice with Cacit and TMP and a low fluoride concentration presented similar results when compared to a dentifrice with 1,100 mg F/g (p>0.05). CONCLUSIONS: Dentifrices with 450 and 1,000 µg F/g, Cacit and TMP were as effective as a gold standard one.

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Published
2012-02-01
Section
Original Articles