• Cristiane Aparecida Moran PhD by Federal University of Sao Paulo - Unifesp, Sao Paulo, Brazil.
  • Roberta de Oliveira Cacho PhD and Adjunct Professor at Federal University of Rio Grande do Norte – UFRN/FACISA, RN, Brazil
  • Enio Walker Azevedo Cacho PhD and Adjunct Professor at Federal University of Rio Grande do Norte – UFRN/FACISA, RN, Brazil
  • Klayton Galante Sousa PhD and Adjunct Professor at Federal University of Rio Grande do Norte – UFRN/FACISA, RN, Brazil
  • Jane Carla de Souza PhD and Adjunct Professor at Federal University of Rio Grande do Norte – UFRN/FACISA, RN, Brazil
  • Gentil Gomes da Fonseca Filho Physiotherapist, Resident at the University Hospital Ana Bezerra, HUAB/EBSERH/UFRN, RN, Brazil
  • Silvana Alves Pereira PhD and Adjunct Professor at Residence at the University Hospital Ana Bezerra and Federal University of Rio Grande do Norte – UFRN/ EBSERH/FACISA, RN, Brazil



acoustic stimulation, therapy, complementary therapies, newborn, underweight baby.


Introduction: Previous studies have shown music therapy as a way to improve the clinical status of premature infants, improving vital signs and decreasing crying episodes. Objective: Compare the effects of music on vital signs of premature infants undergoing respiratory physiotherapy. Methods: We performed a randomized clinical trial consisting of 26 premature infants, divided into control group (N=12) and study group (N=14), carried out in a Neonatal Intensive Care Unit. All newborn infants undergone standard practice physiotherapy for 15 minutes: vibration and aspiration. On the study group they were exposed to classical music three minutes before the standard physiotherapy, and finished three minutes after the end of these procedures. A recorder was placed inside the incubator with an intensity of 25 decibels. Measurements of heart and respiratory rate and oxygen saturation were measured before, during and after each sessions of respiratory physiotherapy for two groups. Results: When comparing control and study groups regarding heart rate frequency and oxygen saturation, there was no statistically significant difference, but the inclusion of music determined clinically the variability of these data and 30% of the variation in respiratory rate was due to the inclusion of music during and after the physiotherapy, and the neonatal noninvasive ventilation showed less variation in their respiratory rate when compared to the neonatal on oxygen therapy. Conclusion: The results have showed a beneficial effect of music, showing lower respiratory rate in newborn infants during and after respiratory physiotherapy procedure.


Yamanouchi I, Fukuhara H, Shimura Y. The transmission of ambient noise and selfgenerated sound in the human body. Acta Pediatr Jpn. 1990; 32(6): 615-24. DOI:

Chou LL, Wang RH, Chen SJ, Pai L. Effects of music therapy on oxygen saturation in premature infants receiving endotracheal suctioning. J Nur Res. 2003;11(3): 209-16.

Batt-Rawden K, Tellnes G. How music may promote healthy behavior. Scand J Public Health. 2011; 39(2):113-20. DOI:

Lubetzky R, Mimouni FB, Dollberg S, Reifen R, Ashbel G, Mandel D. Effect of music by mozart on energy expenditure in growing preterm infants. Pediatrics. 2010; 125(1): e24-e28.DOI:

Olischar M, Shoemark H, Holton T, Weninger M, Hunt RW. The influence of music on aEEG activity in neurologically healthy newborns e” 32 week’s gestational age. Acta Paediatr. 2011; 100(5): 670-75. DOI:

Arnon S, Shapsa A, Forman L, Regev R, Bauer S, Litmanovitz I, et al. Live music is beneficial to preterm infants in the neonatal intensive care unit environment. Birth. 2006; 33(2):131-6. DOI:

Field T, Hernandez-Reif M, Feijo L, Freedman J. Prenatal, perinatal and neonatal stimulation: a survey of neonatal nurseries. Infant Behav Dev. 2006; 29(1):24-31. DOI:

Standley J. Music therapy research in the NICU: an updated meta-analysis. Neonatal Netw. 2012; 31(5): 311-16. DOI:

Rahlin M, Stefani J. Effects of music on crying behavior of infants and toddlers during physical therapy intervention. Pediatr Phys Ther. 2009; 21(4):325-335. DOI:

Keith DR, Russel K, Weaver BS. The Effects of music listening on inconsolable crying in premature infants. J Music Ther. 2009; 46(3): 191-203. DOI:

Silva CM, Cação JMR, Silva KCS, Marques CF, Merey LSF. Respostas fisiológicas de recémnascidos pré-termo submetidos à musicoterapia clássica. Rev Paul Pediatr. 2013;31(1):30-6. DOI:


Diniz NF, Gomes ELFD, Moran CA, Pereira SA, Martins LMA, Pereira LC. Assessment of the effects of manual chest compression technique on atelectasis in infants: a randomized clinical trial. Int J Clin Med. 2014; 5(9): 507-513. DOI:

Pereira SA, Moran CA. Estimulação visual precoce para recém-nascidos prematuros internados na unidade neonatal. [cited 2015 Jun 18] Available from: 5856&fase=imprime.

Sola A, Dieppa FD, Rogido MR. An evident view of evidence-based practice in perinatal medicine: absence of evidence is not evidence of absence. J Pediatr. 2007; 83(5):395-414. DOI:

Main E, Castle R, Newham D, Stocks J. Respiratory physiotherapy vs. suction: the effects on respiratory function in ventilated infants and children. Intensive Care Med. 2004; 30(6):1144-51. DOI:


Trevarthen C, Malloch SN. The dance of wellbeing: defining the musical therapeutic effect. Nordic Journal of Music Therapy. 2000; 9(2): 3-17. DOI:

Shoemark H. Contingent singing: The musicality of companionship with the hospitalized newborn infant. In: Baker F, Uhlig S. Therapeutic voicework in music therapy. 2011; p. 229-49.

Butt ML, Kisilevsky BS. Music modulates behavior of premature infants following heel lance. Can J Nurs Res. 2000; 31(4): 17-39.

Beebe B, Jaffe J, Lachmann F, Feldstein S, Crown C, Jasnow M. Systems models in development and psychoanalysis: The case of vocal rhythm coordination and attachment. Infant Mental Health J. 2000; 21(1-2): 99-122.


Carroll JL. Invited review: developmental plasticity in respiratory control. J Appl Physiol. 2003; 94(1): 375-389 DOI:

Hatem TP, Lira PIC, Mattos SS. The therapeutic effects of music in children following cardiac surgery. J Pediatr. 2006; 82(3): 186-92. DOI:

Yildiz A, Arikan D. The effects of giving pacifiers to premature infants and making them listen to lullabies on their transition period for total oral feeding and sucking success. J Clin Nurs. 2012; 21(5-6): 644-56. DOI:

O’Gorman S. Infant-Directed singing in neonatal and paediatric intensive care. Austr New Zealand J Family Ther. 2007; 28(2):100-8. DOI:

Gilad E, Arnon S. The role of live music and singing as a stress-reducing modality in the neonatal intensive care unit environment. Music Med 2010; 2(1):18-22. DOI:

Lubetzky R, Mimouni FB, Dolberg S, et al. Effect of music by Mozart on energy expenditure in growing preterm infants. Pediatrics 2010; 125 (1): e24-8.

Aydin D, Yildiz S. Effect of classical music on stress among preterm infants in a neonatal intensive care unit. Health Med. 2012; 6(9): 3162-3168.

Malloch SS, Shoemark H, Èrnèec R, Newnham C, Paul C, et al. Music therapy with hospitalized infants—the art and science of communicative musicality. Infant Ment Health J. 2012; 33(4): 386-399. DOI:

Krueger C. Exposure to maternal voice in preterm infants: a review. Adv Neonatal Care. 2010; 10(1):13-20. DOI:

Hodges AL,Wilson LL. Effects of music therapy on preterm infants in the neonatal intensive care unit. Altern Ther Health Med. 2010; 16(5): 72-73.

Johnston C, Campbell-Yeo M, Rich B, Whitley J, Filion F, Cogan J, et al. Therapeutic touch is not therapeutic for procedural pain in very preterm neonates: a randomized trial. Clin J Pain. 2013; 29(9): 824-9. DOI:





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