Knowledge and acceptance of HPV vaccine among adolescents, parents and health professionals: construct development for collection and database composition

Autores

  • Priscila Dantas Leite e Sousa Laboratório de Delineamento de Estudo e Escrita Científica, Faculdade de Medicina do ABC, Santo André- SP
  • Albertina Duarte Takiuti Disciplina de Ginecologia da Faculdade de Medicina da Universidade de São Paulo (USP)– São Paulo-
  • Edmund Chada Baracat Disciplina de Ginecologia da Faculdade de Medicina da Universidade de São Paulo (USP)–São Paulo
  • Isabel Cristina Esposito Sorpreso Laboratório de Delineamento de Estudo e Escrita Científica, Faculdade de Medicina do ABC, Santo André- SP/ Disciplina de Ginecologia da Faculdade de Medicina da Universidade de São Paulo (USP)–São Paulo
  • Luiz Carlos de Abreu Laboratório de Delineamento de Estudo e Escrita Científica, Faculdade de Medicina do ABC, Santo André- SP

DOI:

https://doi.org/10.7322/jhgd.143856

Palavras-chave:

HPV, papillomavirus vaccines, knowledge, adolescent, parents, health-care professional, surveys and questionnaires

Resumo

Introduction: The human papillomavirus (HPV) is a prevalent viral infection in the sexually active population, which can be oncogenic and non-oncogenic. Educational efforts by health professionals, aimed at adolescents and their parents, help decision-making on human papillomavirus vaccination, benefiting the implantation process and vaccine coverage.

Objective: To describe the data collection constructs about knowledge and acceptability of HPV vaccine among adolescents, parents and health professionals.

Methods: Study of construct elaboration based on an empirical review of the literature with a qualitative focus on PubMed database, from 2007 to 2014, using the following keywords: Papillomaviridae AND Papillomavirus Vaccines AND Knowledge AND Community Health Services. A total of 31 questions were divided into six categories. In the internal validation, the final construct was applied in 390 subjects (adolescents, parents/guardians and health professionals) in the period of 2014. The proportion of assertive responses and respective 95% confidence interval (CI) were used to describe each question.

Results: Three articles on the subject were found in the databases consulted that served as the basis for the elaboration of the questionnaire. There was a lower proportion of correct answers among adolescents about knowledge of HPV. Adolescents, parents, and carers showed a low proportion of correctness about the safety and efficacy of the vaccine. The three groups did not show any barriers to vaccine acceptability.

Conclusion: The instrument was adequate to measure knowledge about HPV, its repercussions and its vaccine among adolescents, parents/guardians and health professionals, as well as measuring the acceptability of the human papillomavirus vaccine.


Referências

Forman D, Martel C, Lacey CJ, Soerjomataram I, Lortet-Tieulent J, Bruni L, et al. Global burden of human papillomavirus and related diseases. Vaccine. 2012;30( Suppl 5):F12-23. DOI: http://dx.doi.org/10.1016/j.vaccine.2012.07.055

Human papillomavirus vaccines: WHO position paper, October 2014. Wkly Epidemiol Rec. 2014;89(43):465-91.

Brasil. Ministério da Saúde. Incidência de câncer no Brasil: estimativa/2016. Brasília: Instituto Nacional do Câncer. [cited 2017 oct 16] Available from: http://www.inca.gov.br/estimativa/2016/estimativa-2016-v11.pdf.

Dillner J, Kjaer SK, Wheeler CM, Sigurdsson K, Iversen OE, Hernandez-Avila M, et al. Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial. BMJ. 2010;341:c3493. DOI: https://doi.org/10.1136/bmj.c3493

Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância de Doenças Transmissíveis. Coordenação-Geral do Programa Nacional de Imunizações. Informe Técnico da vacina Papiloma vírus humano 6, 11, 16 e 18 (recombinante). Brasília: Ministério da Saúde, 2015.

Kilic A, Seven M, Guvenc G, Akyuz A, Ciftci S. Acceptance of human papillomavirus vaccine by adolescent girls and their parents in Turkey. Asian Pac J Cancer Prev. 2012;13(9):4267-72. DOI: http://dx.doi.org/10.7314/APJCP.2012.13.9.4267

Phan DP, Pham QT, Strobel M, Tran DS, Tran TL, Buisson Y. Acceptability of vaccination against Human Papillomavirus (HPV) by pediatricians, mothers and young women in Ho Chi Minh City, Vietnam. Rev Epidemiol Sante Publique. 2012;60(6):437-46. DOI: http://dx.doi.org/10.1016/j.respe.2012.03.010

Kwan TT, Chan KK, Yip AM, Tam KF, Cheung AN, Young PM, et al. Barriers and facilitators to human papillomavirus vaccination among Chinese adolescent girls in Hong Kong: a qualitative-quantitative study. Sex Transm Infect. 2008;84(3):227-32. DOI: http://dx.doi.org/10.1136/sti.2007.029363

Kornfeld J, Byrne MM, Vanderpool R, Shin S, Kobetz E. HPV knowledge and vaccine acceptability among Hispanic fathers. J Prim Prev. 2013;34(0):59-69. DOI: http://dx.doi.org/10.1007/s10935-013-0297-0

Figueroa‐Downing D, Baggio M, Baker ML, Chiang EDO, Villa LL, Eluf Neto J, et al. Factors influencing HPV vaccine delivery by healthcare professionals at public health posts in São Paulo, Brazil. Int J Gynaecol Obstet. 2017;136(1):33-9. DOI: http://dx.doi.org/10.1002/ijgo.12004

Osis MJD, Duarte GA, de Sousa MH, Conhecimento e atitude de usuários do SUS sobre o HPV e as vacinas disponíveis no Brasil. Rev Saúde Pública. 2014; 48(1):123-33. DOI: http://dx.doi.org/10.1590/S0034-8910.2014048005026

Colucci MZO, Alexandre NMC, Milani D. Construção de instrumentos de medida na área da saúde. Ciênc Saúde Coletiva. 2015;20(3):925-36. DOI: http://dx.doi.org/10.1590/1413-81232015203.04332013

Merriam SB. Qualitative research and case study applications in education. San Francisco (USA): Jossey-Bass, 1998; p.179.

Yin RK. Estudo de caso: planejamento e métodos. 3ed. Porto Alegre: Bookman, 2005; p. 212.

World Health Organization (WHO). Young people´s health - a challenge for society. Geneva: WHO, 1986.

Giambi C, D'Ancona F, Del Manso M, De Mei B, Giovannelli I, Cattaneo C, et al. Exploring reasons for non-vaccination against human papillomavirus in Italy. BMC Infect Dis. 2014;14:545. DOI: http://dx.doi.org/10.1186/s12879-014-0545-9

Fu CJ, Pan XF, Zhao ZM, Saheb-Kashaf M, Chen F, Wen Y, et al. Knowledge, perceptions and acceptability of HPV vaccination among medical students in Chongqing, China. Asian Pac J Cancer Prev. 2014;15(15):6187-93. DOI: http://dx.doi.org/10.7314/APJCP.2014.15.15.6187

Rosberger Z, Krawczyk A, Stephenson E, Lau S. HPV vaccine education: enhancing knowledge and attitudes of community counselors and educators. J Cancer Educ. 2014;29(3):473-77.DOI:http://dx.doi.org/10.1007/s13187-013-0572-z

Mazzadi A, Paolino M, Arrossi S. HPV vaccine acceptability and knowledge among gynecologists in Argentina. Salud Publica Mex. 2012;54(5):515-22. DOI: http://dx.doi.org/10.1590/S0036-36342012000500008

Poole DN, Tracy JK, Levitz L, Rochas M, Sangare K, Yekta S, et al. A cross-sectional study to assess hpv knowledge and HPV vaccine acceptability in mali. PLoS One. 2013;8(2):e56402. DOI: https://doi.org/10.1371/journal.pone.0056402

Maia TQ, Soares LO, Valle PASS, Medeiros VMG. Educação para sexualidade de adolescentes: experiência de graduandas. Nexus Rev Extensão IFAM, 2016;2(2):71-8.

Domingues CMAS, Alvarenga AT. Identidade e sexualidade no discurso adolescente. Rev Bras Cresc Desenvolv Hum. 1997;7(2):36-63. DOI: http://dx.doi.org/10.7322/jhgd.38564

De Groot AS, Tounkara K, Rochas M, Beseme S, Yekta S, Diallo FS, et al. Knowledge, attitudes, practices and willingness to vaccinate in preparation for the introduction of HPV vaccines in Bamako, Mali. PloS One. 2017;12(2):e0171631. DOI: https://doi.org/10.1371/journal.pone.0171631

Zouheir Y, Daouam S, Hamdi S, Alaoui A, Fechtali T. Knowledge of human papillomavirus and acceptability to vaccinate in adolescents and young adults of the Moroccan population. J Pediatr Adolesc Gynecol. 2016;29(3):292-8. DOI: http://dx.doi.org/10.1016/j.jpag.2015.11.002

World Health Organization (WHO). Monitoring tobacco use and prevention policies. Report on the global tobacco epidemic, 2017. Geneva: World Health Organization; 2017.

International Collaboration of Epidemiological Studies of Cervical Cancer, Appleby P, Beral V, González AB, Colin D, Franceschi S, et al. Carcinoma of the cervix and tobacco smoking: collaborative reanalysis of individual data on 13,541 women with carcinoma of the cervix and 23,017 women without carcinoma of the cervix from 23 epidemiological studies. Int J Cancer. 2006; 118(6):1481-95. DOI: http://dx.doi.org/10.1002/ijc.21493

Read DS, Joseph MA, Polishchuk V, Suss AL. Attitudes and perceptions of the HPV vaccine in Caribbean and African-American adolescent girls and their parents. J Pediatr Adolesc Gynecol. 2010;23(4):242-5. DOI: http://dx.doi.org/10.1016/j.jpag.2010.02.002

Wang LDL, Lam WWT, Fielding R. Determinants of human papillomavirus vaccination uptake among adolescent girls: A theory-based longitudinal study among Hong Kong Chinese parents. Prev Med. 2017;102:24-30. DOI: http://dx.doi.org/10.1016/j.ypmed.2017.06.021

Reiter PL, Brewer NT, Gottlieb SL, McRee AL, Smith JS. Parents’ health beliefs and HPV vaccination of their adolescent daughters. Soc Sci Med. 2009;69(3):475-80. DOI: http://dx.doi.org/10.1016/j.socscimed.2009.05.024

Ogilvie GS, Remple VP, Marra F, McNeil SA, Naus M, Pielak KL, Ehlen TG, Dobson SR, Money DM, Patrick DM. Parental intention to have daughters receive the human papillomavirus vaccine. CMAJ. 2007;177(12):1506-12. DOI: http://dx.doi.org/10.1503/cmaj.071022

Chan SSC, Ng BHY, Lo WK, Cheung TH, Chung TKH. Adolescent girls’ attitudes on human papillomavirus vaccination. J Pediatr Adolesc Gynecol. 2009;22(2):85-90. DOI: http://dx.doi.org/10.1016/j.jpag.2007.12.007

Markowitz LE, Tsu V, Deeks SL, Cubie H, Wang SA, Vicari AS, et al. Human papillomavirus vaccine introduction-the first five years. Vaccine. 2012;30(Suppl.5):139-48. DOI: http://dx.doi.org/10.1016/j.vaccine.2012.05.039

Chehuen Neto JA, Braga NAC, Campos JD, Rodrigues RR, Guimarães KG, Sena ALS, et al. Atitudes dos pais diante da vacinação de suas filhas contra o HPV na prevenção do câncer de colo do útero. Cad Saúde Coletiva. 2016; 24(2):248-251. DOI: http://dx.doi.org/10.1590/1414-462X201600020275

Madhivanan P, Krupp K, Yashodha MN, Marlow L, Klausner JD, Reingold AL. Attitudes toward HPV vaccination among parents of adolescent girls in Mysore, India. Vaccine. 2009;27(38):5203-8. DOI: http://dx.doi.org/10.1016/j.vaccine.2009.06.073

Grandahl M, Tydén T, Westerling R, Nevéus T, Rosenblad A, Hedin E, et al. To Consent or Decline HPV Vaccination: A Pilot Study at the Start of the National School‐Based Vaccination Program in Sweden. J Sch Health. 2017;87(1):62-70. DOI: http://dx.doi.org/10.1111/josh.12470

Albright K, Barnard J, O'Leary ST, Lockhart S, Jimenez-Zambrano A, Stokley S, et al. Noninitiation and Noncompletion of HPV Vaccine Among English-and Spanish-Speaking Parents of Adolescent Girls: A Qualitative Study. Acad Pediatr. 2017;17(7):778-84. DOI: http://dx.doi.org/10.1016/j.acap.2017.03.013

Cheruvu VK, Bhatta MP, Drinkard LN. Factors associated with parental reasons for “no-intent” to vaccinate female adolescentes with human papillomavirus vaccine: National Immunization Survey Teen-2008-2012. BMC Pediatr. 2017;17:52. DOI: http://dx.doi.org/10.1186/s12887-017-0804-1

McRee AL, Gilkey MB, Dempsey AF. HPV vaccine hesitancy: findings from a statewide survey of health care providers. J Pediatr Health Care. 2014;28(6):541-9. DOI: http://dx.doi.org/10.1016/j.pedhc.2014.05.003

Nunes CBL, Arruda KM, Pereira TN. Apresentação da eficácia da vacina HPV distribuída pelo sus a partir de 2014 com base nos Estudos Future I, Future II, e Villa et al. Acta Biomed Brasiliensia. 2015;6(1):1-9.

Harper DM, DeMars LR. HPV vaccines–A review of the first decade. Gynecol Oncol. 2017;146(1):196-204. DOI: http://dx.doi.org/10.1016/j.ygyno.2017.04.004

Head KJ, Vanderpool RC, Mills LA. Health care providers' perspectives on low HPV vaccine uptake and adherence in Appalachian Kentucky. Public Health Nurs. 2013;30(4):351-60. DOI: http://dx.doi.org/10.1111/phn.12044

Dochez C, Bogers JJ, Verhelst R, Rees H. HPV vaccines to prevent cervical cancer and genital warts: an update. Vaccine. 2014;32(14):1595-1601. DOI: http://dx.doi.org/10.1016/j.vaccine.2013.10.081

Stormo AR, Moura L, Saraiya M. Cervical cancer-related knowledge, attitudes, and practices of health professionals working in brazil’s network of primary care units. Oncologist. 2014;19(4):375-82. DOI: http://dx.doi.org/10.1634/theoncologist.2013-0318

Bezerra IMP, Sorpreso ICE. Conceitos de saúde e movimentos de promoção da saúde em busca da reorientação de práticas. J Hum Growth Dev. 2016,26(1):11-20. DOI: http://dx.doi.org/10.7322/jhgd.113709

Cunningham M, Davison C, Aronson K. HPV vaccine acceptability in Africa: a systematic review. Prev Med. 2014;69:274-9. DOI: http://dx.doi.org/10.1016/j.ypmed.2014.08.035

Hendry M, Lewis R, Clements A, Damery S, Wilkinson C. "HPV? Never heard of it!": a systematic review of girls' and parents' information needs, views and preferences about human papillomavirus vaccination. Vaccine. 2013;31(45):5152-67. DOI: http://dx.doi.org/10.1016/j.vaccine.2013.08.091

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Publicado

2018-03-12

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v. 28 n. 1 (2018)

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