Perspectivas sobre o uso de modelos murinos da síndrome de down em pesquisas translacionais envolvendo função visual e motora

Autores

  • Alberto Costa Case Western Reserve University, Cleveland, OH
  • Dafne Herrero University of São Paulo

DOI:

https://doi.org/10.7322/jhgd.81288

Palavras-chave:

síndrome de down, modelos murinos, pesquisas translacionais

Resumo

Não se aplica

Biografia do Autor

  • Alberto Costa, Case Western Reserve University, Cleveland, OH
    Division of Pediatric Neurology, Department of Pediatrics, Case Western Reserve University, Cleveland, OH, United States
  • Dafne Herrero, University of São Paulo
    Department of Maternal and Child Health, School of Public Health, University of São Paulo, Sao Paulo, Brazil.

Referências

Patterson D, Costa AC. Down syndrome and genetics - a case of linked histories. Nat Rev Genet. 2005 Feb;6(2):137-47. Review. No abstract available.

IBGE. Net 2010. Pessoas com deficiência. Disponível em <http://www.ibge.com.br/home/>. Acesso em: 3 jan 2000.

Parker SE, Mai CT, Canfield MA, Richard R, Wang Y, Meyer RE, Anderson P, Mason CA, Collins JS, Kirby RS, Correa A. Updated National Birth Prevalence estimates for selected birth defects in United States 2004-2006. National Birth Defects Prevention Network. 2010 Dec, 88(12):1008-16. Doi: 10.1002/bdra.20735.

Pavarino BEC, Biselli JM, Bonfim D, Goloni-Bertollo EM. Clinical profile of children with down syndrome treated in a genetics outpatient service in the southeast of Brazil. Rev. Assoc. Med. Bras. [serial on the Internet]. 2009, 55(5): 547-552.

Zigman WT, Lott IT. Alzheimer's disease in Down syndrome: neurobiology and risk. Ment Retard Dev Disabil Res Rev. 2007; 13(3):237-46.

Caputo AR, Wagner RS, Reynolds DR, Guo SQ, Goel AK. Down syndrome. Clinical review of ocular features.Clin Pediatr (Phila). 1989 Aug;28(8):355-8.

Courage ML, Adams RJ, Hall EJ. Contrast sensitivity in infants and children with Down syndrome. Vis Res. 1997; 37: 1545-1555.

Cregg M, Woodhouse JM, Stewart RE, Pakeman VH, Bromham NR, Gunter HL, Trojanowska L, Parker M, Fraser WI. 2003. Decelopment of refractive error and strabismus in children with Down syndrome. Invest Ophthalmol Vis Sci 44:1023-1030.

John FM, Bromham NR, Woodhouse JM, Candy TR. Spatial vision deficits in infants and children with Down syndrome. Invest Ophthalmol Vis Sci 2004;45:1566–1572.

Costa ACS. An assessment of the vestibulo-ocular reflex (VOR) in persons with Down syndrome.Exp Brain Res. 2011 Oct;214(2):199-213. doi: 10.1007/s00221-011-2820-y. Epub 2011 Aug 13.

Costa ACS. An assessment of optokinetic nystagmus (OKN) in persons with Down syndrome. Exp Brain Res. 2011 Oct;214(3):381-91. doi: 10.1007/s00221-011-2834-5. Epub 2011 Aug 14.

Latash M, Wood L, Ulrich D. What is the currently known about hypotonia, motor skill development and physical activity in Down syndrome. Doi: 103104/reviews2074. 2008.

Latash M. Neurophysiologic Basis of Movement. 1998.

Ulrich Da, Wu Looper, Algulo-Barroso RM. Effects of various treadmill interventions on the development of joint kinematics in infants with Down syndrome. Phys Ther, 2010; Sep 90(9):1265-76. Doi: 10.2522.

Costa AC, Scott-McKean JJ. Prospects for improving brain function in individuals with Down syndrome. CNS Drugs. 2013 Sep;27(9):679-702. DOI: 10.1007/s40263-013-0089-3.

Costa AC, Siddiqui A, Lacroix T, Stasko MR, Scott-McKean JJ, Gardiner KJ. Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801.Genes Brain Behav. 2008 Oct; 7(7):810-20. Doi: 10.1111/j.1601-183X.2008.00428.x.

Lockrow J, Borger H, Bimonte-Nelson H, Granholm AC. Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome. Behav Brain Res. 2011 Aug 10; 221(2):610-22. Doi: 10.1016/j.bbr.2010.03.036.

Rueda N, Llorens-Martín M, Florez J, Valdizan E, Banerjee P, Trejo JL, Martinez-Cue C. Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome. J Alzheimer Dis. 2010; 21(1):277-90. Doi: 10.3233/JAD-2010-100240.

Figueiredo JL, Vinegoni C, de Abreu LC. Perinatal health and translational medicine. Journal of Human Growth and Development. 2013; 23(2): 125-127.

Boada R, Huttaf Lee C, Schrader A, Weitzenkamp D, Benke TA, Goldson EJ, Costa AC. Antagonism of NMDA receptors as a potential treatment for Down’s syndrome: a pilot randomized controlled trial. Translational Psychiatry, 2012, 2, e141.

Costa AC, Walsh K, Davisson MT. Motor dysfunction in mouse model for Down syndrome. Physiol Behav. 1999 Dec 1-15;68(1-2):211-20.

Hampton TG, Stasko MR, Kale A, Amende I, Costa AC. Gait dynamics I trisomic mice: quantitative neurological traits of Down syndrome. Physiol Behav. 2004 Sep 15; 82(2-3):381-9.

Scott-McKean JJ,Chang B, Hurd RE, Nusinowitz S, Schmidt C, Davisson MT, Costa ACS. The Mouse Model of Down Syndrome Ts65Dn Presents Visual Deficits as Assessed by Pattern Visual Evoked Potentials. Invest Ophthalmol Vis Sci. 2010 June; 51(6): 3300–3308. doi: 10.1167/iovs.09-4465.

Rachubinski Al, Maclean KN, Evans JR, Bjugstad KB. Modulating cognitive deficits and tau accumulation in a mouse of aging Down syndrome through neonatal implantation of neural progenitor cells. Exp Gerontol. 2012 Sep; 47(9):723-33. Doi: 10.1016/j.exger.2012.06.013.

Gutierrez-Castellanos N, Winkelman BH, Tolosa-Rodriguez L, De Gruijl JR, De Zeeuw CI. Impact of aging on long -term ocular reflex adaptation. Neurobiol Aging. 2013 Dec; 34(12): 2784-92. Doi: 10.1016/j.neurobiolaging.2013.06.012.

Pinheiro RC, Martinez CMS, Fontaine AMGV. Visual motor integration and overall development of preterm and at term children at the beginning of schooling, Journal of Human Growth and Development. 2014; 24(2): 181-187.

Rocha ES, Rose GJ, Schivinski CIS. Level of physical activity and functional in athletes children. Journal of Human Growth and Development. 2014; 24(2): 127-134.

Downloads

Publicado

2014-06-01

Edição

v. 24 n. 2 (2014)

Seção

Editorial

Licença

CODE OF CONDUCT FOR JOURNAL  PUBLISHERS

 

Publishers who are Committee on Publication Ethics members and who support COPE membership for journal editors should:

 

Publishers should:

 

  • Define the relationship between publisher, editor and other parties in a contract
  • Respect privacy (for example, for research participants, for authors, for peer reviewers)
  • Protect intellectual property and copyright
  • Foster editorial independence

 

Publishers should work with journal editors to:

 

  • Set journal policies appropriately and aim to meet those policies, particularly with respect to:

–         Editorial  independence

–         Research ethics, including confidentiality, consent, and the special requirements for human and animal research

–         Authorship

–         Transparency and integrity (for example, conflicts of interest, research funding, reporting standards

–         Peer review and the role of the editorial team beyond that of the journal editor

–         Appeals and complaints

  • Communicate journal policies (for example, to authors, readers, peer reviewers)
  • Review journal policies periodically, particularly with respect to new recommendations from the COPE
  • Code of Conduct for Editors and the COPE Best Practice Guidelines
  • Maintain the integrity of the academic record
  • Assist the parties (for example, institutions, grant funders, governing bodies) responsible for the investigation of suspected research and publication misconduct and, where possible, facilitate in the resolution of these cases
  • Publish corrections, clarifications, and retractions
  • Publish content on a timely basis