Quality of life, anxiety and depression in head and neck cancer patients: a randomized clinical trial





Head and Neck Neoplasms, Self Care, Health Education, Quality of Life, Anxiety, Oncology Nursing Inhalation


BJECTIVE To evaluate an educational program based on the principles of self-management with a conventional educational program through quality of life, anxiety and depression instruments within 12 months of starting cancer treatment. METHOD An experimental, randomized, controlled study conducted with head and neck cancer patients treated at a university hospital in the city of São Paulo, Brazil. Patients were randomly divided into two groups: the control group submitted to the conventional educational plan, and the experimental group submitted to the educational plan for self-management. Descriptive and analytical statistics were used for the analyzes using the t-test, Fischer’s exact test and Repeated Measures ANOVA. RESULTS Twenty (20) patients were selected. Most participants were male, in advanced stages of disease and undergoing three therapeutic modalities. The control group showed a gradual decrease in quality of life scores during treatment, while the experimental group progressively increased. The correlation was significant between the presence of anxiety and depression symptoms and poor quality of life. Patients in the control group had a significant worsening in social/family well-being (P = 0.02) and the prevalence of additional head and neck cancer-related additional concerns (P = 0.01), while the experimental group had reduced anxiety symptoms (P = 0.001) and improved emotional well-being (P = 0.01). CONCLUSION The educational intervention based on building self-management skills favored quality of life and reduced anxiety and depression. Brazilian Registry of Clinical Trials (RBR 2q53ct).


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How to Cite

Hortense, F. T. P., Bergerot, C. D., & Domenico, E. B. L. D. (2021). Quality of life, anxiety and depression in head and neck cancer patients: a randomized clinical trial. Revista Da Escola De Enfermagem Da USP, 54, e03546. https://doi.org/10.1590/s1980-220x2018040103546



Original Article