Hepatite C
revisão dos medicamentos utilizados no tratamento
DOI:
https://doi.org/10.11606/issn.1679-9836.v98i5p341-348Palavras-chave:
Hepatite C, Tratamento farmacológico, Interferons, Literatura de revisão como assunto, DiagnósticoResumo
O objetivo deste trabalho foi realizar uma revisão da literatura sobre os fármacos utilizados para o tratamento da hepatite C desde a descoberta do vírus, em 1989. Para atingir esse objetivo, foi realizada uma pesquisa nas bases Medline e SciELO, utilizando o termos “hepatite C”, “tratamento”, “livre de interferon”, “revisão” e “ensaio clínico”. Este trabalho apresenta uma revisão das características gerais da hepatite C juntamente com sua epidemiologia e diagnóstico. Durante muito tempo, a única opção disponível para o tratamento da hepatite C foi o interferon. Esta droga não mostrou boa eficácia e seu uso foi minimizado com o surgimento de novos regimes sem interferon que aumentaram a taxa de sucesso para algo em torno de 95%. Tais medicamentos permitiram o alcance real da cura do vírus, embora estejam disponíveis no Sistema Único de Saúde (SUS) brasileiro, são tratamentos caros que restringem o acesso a grande parte da população infectada.
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