Impacto da técnica anestésica no comportamento evolutivo do câncer de mama: uma revisão sistemática de literatura
DOI:
https://doi.org/10.11606/issn.1679-9836.v100i1p35-40Palavras-chave:
Revisão sistemática, Câncer de mama, Mastectomia, Anestesia localResumo
Apesar de ser uma importante abordagem para o tratamento do câncer de mama, a cirurgia pode paradoxalmente favorecer a progressão tumoral, apesar da intenção curativa. Como as técnicas de anestesia local podem ser uma oportunidade terapêutica para reduzir a manutenção e dispersão neoplásica, o objetivo do estudo foi avaliar seus efeitos no comportamento evolutivo do câncer de mama no contexto clínico. Trata-se de uma revisão sistemática de literatura a partir da base de dados PubMed com os descritores MeSH “mastectomy”, “mastectomy, radical”, “anesthesia, local”, “recurrence”, “neoplasm recurrence, local”. Foram selecionados seis artigos, sendo a maioria retrospectivo e apenas um estudo controlado randomizado. Entre as diferenças discutidas na análise de variáveis, critérios de inclusão e resultados observados, cinco estudos não apresentaram efeito sobre o comportamento evolutivo do câncer de mama. Assim, apesar dos potenciais benefícios da anestesia local sobre o comportamento evolutivo do câncer de mama, essa revisão não encontrou evidência suficiente para apoiar essa intervenção para a prática clínica. Apesar disso, pode reduzir o consumo de opioide e prover uma opção viável para o manejo da dor, que pode melhorar a qualidade de vida das pacientes.
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Copyright (c) 2021 Marcela Chagas Lima Mussi, Arthur Giovane Campos Batista, Clécio Ênio Murta de Lucena
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