Eficácia dos benzodiazepínicos no tratamento de transtornos ansiosos: uma revisão de literatura

Autores

DOI:

https://doi.org/10.11606/issn.1679-9836.v101i6e-194499

Palavras-chave:

Psicologia, Psiquiatria, Psicofarmacologia, Benzodiazepínicos, Ansiedade

Resumo

Com o crescente índice de transtornos ansiosos na população mundial, cresce a necessidade de se investigar psicofármacos que possibilitem experiências de tratamento, segurança e sustentabilidade ao paciente. Dessa forma, o objetivo desta pesquisa é realizar uma revisão sistemática metodológica acerca da eficácia dos benzodiazepínicos (BZ) para o tratamento de transtornos ansiosos (TA). Os estudos foram pesquisados nas bases de dados da PubMed e ScienceDirect, a partir dos descritores: “benzodiazepines” e “anxiety disorder”. Será utilizado o operador booleano “AND”. Foram revisados 27 artigos científicos, com amostra total de 120.418 pacientes de estudos publicados entre os anos de 2011 e 2021, sendo 15 revisões sistemáticas, 5 revisões sistemáticas com meta-análise, 2 meta-análises, 1 revisão sistemática com estudo original, 1 ensaio clínico, 1 ensaio clínico com caso controle, 1 ensaio clínico com estudo prospectivo e 1 estudo duplo cego com ensaio clínico utilizando placebo. Percebeu-se que os BZ se mostraram efetivos no tratamento de transtornos ansiosos (ansiedade generalizada e fobia social), mas inviável em termos de qualidade e seguridade em relação ao seu potencial de dependência a longo prazo. Novos medicamentos foram considerados como possível substituição do BZ para os TA. Novos estudos considerando outros transtornos ansiosos são necessários, além dos que foram abordados nesta pesquisa.

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Biografia do Autor

  • Gabriel Luiz de Jesus Ribeiro, Centro Universitário Atenas - UniAtenas

    Centro Universitário Atenas, Department of Psychology. 

  • Josué da Silva Brito, Faculdade Atenas - Passos/MG

    Médico. Professor do Departamento de Clínica Médica da Faculdade Atenas - Passos/MG. 

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Publicado

2022-11-29

Edição

Seção

Artigos de Revisão/Review Articles

Como Citar

Eficácia dos benzodiazepínicos no tratamento de transtornos ansiosos: uma revisão de literatura. (2022). Revista De Medicina, 101(6), e-194499. https://doi.org/10.11606/issn.1679-9836.v101i6e-194499