Fatores que influenciam a infecção por H. Pylori e a ocorrência de câncer gástrico: uma revisão sistemática
DOI:
https://doi.org/10.11606/issn.1679-9836.v102i3e-199415Palavras-chave:
Helicobacter pylori, Neoplasias gástricas, Fatores de riscoResumo
Introdução: Dentre os fatores de risco para o câncer gástrico se destaca a infecção por H. pylori. Assim, objetiva-se compilar essa relação e os fatores que a influenciam de maneira sistemática para facilitar seu acesso e entendimento. Material e métodos: Trata-se de uma revisão sistemática. As buscas foram realizadas nas bases de dados PubMed, LILACS e SciELO. Foram incluídos artigos originais nas línguas inglesa, portuguesa e espanhola e excluídos artigos de revisão, cartas e editoriais. Resultados: Nos 15 estudos incluídos, verificou-se a investigação de 14 possíveis fatores que influenciam a relação entre a infecção por H. pylori e o desenvolvimento de câncer gástrico: gênero/sexo, idade, local de residência, consumo de álcool, de tabaco, de frutas e vegetais, suplementação com vitamina C, com vitamina E, com selênio, com ferro e com óleo de alho, tratamento farmacológico contra H. pylori, dispepsia e diabetes mellitus tipo 2. Discussão: Notou-se alta associação entre a infecção por H. pylori e a carcinogênese gástrica, assim como a interferência da dispepsia, diabetes mellitus tipo 2, depleção de ferro, hábitos de vida e dietéticos nessa relação. Conclusão: Portanto, a infecção por H. pylori se caracteriza como instrumento de desencadeamento e progressão dessa patologia.
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Copyright (c) 2023 Maria Fernanda de Almeida Cavalcante Aranha, Ana Beatriz Dias Silva, Isabela de Nazaré Tavares Cardoso Souza, Rita de Cássia Silva de Oliveira
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