Neuromuscular blockade in children

Authors

  • João Fernando Lourenço de Almeida University of São Paulo; Faculty of Medicine; Hospital das Clínicas; Department of Pediatrics
  • W. Jorge Kalil Filho University of São Paulo; Faculty of Medicine; Hospital das Clínicas; Department of Pediatrics
  • Eduardo J. Troster University of São Paulo; Faculty of Medicine; Hospital das Clínicas; Department of Pediatrics

DOI:

https://doi.org/10.1590/S0041-87812000000300007

Keywords:

Neuromuscular blocking age, Neuromuscular blocking dr, Neuromuscular junct, Neuromuscular bl, Neon, Inf, Ch

Abstract

Neuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and adults, and moreover to discuss their indications in critically ill pediatric patients. Continuous improvement of knowledge about NMBAs pharmacology, adverse effects, and the many other remaining unanswered questions about neuromuscular junction and neuromuscular blockade in children is essential for the correct use of these drugs. Therefore, the indication of these agents in pediatrics is determined with extreme judiciousness. Computorized (Medline 1990-2000) and active search of articles were the mechanisms used in this review.

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Published

2000-06-01

Issue

Vol. 55 No. 3 (2000)

Section

Review

How to Cite

Almeida, J. F. L. de, Kalil Filho, W. J., & Troster, E. J. (2000). Neuromuscular blockade in children . Revista Do Hospital Das Clínicas, 55(3), 105-110. https://doi.org/10.1590/S0041-87812000000300007