Widespread hematogenous metastases and Trousseau's syndrome in gastric adenocarcinoma


  • Vitorino Modesto dos Santos Triângulo Mineiro Medical School
  • Denise Bertulucci Rocha Rodrigues Triângulo Mineiro Medical School
  • Eumênia Costa da Cunha Castro Triângulo Mineiro Medical School
  • João Carlos Saldanha Triângulo Mineiro Medical School
  • Sheila Soares Triângulo Mineiro Medical School
  • Vicente de Paula Antunes Teixeira Triângulo Mineiro Medical School
  • Marlene Antônia dos Reis Triângulo Mineiro Medical School




Trousseau's syndrome, Disseminated intravascular coagulation, Subdural hematoma, Gastric cancer, Krukenberg tumor


A case of widespread hematogenous metastases and Trousseau's syndrome is reported in a 40 year-old white housewife with gastric cancer, presenting subdural hematoma, ecchymoses, epistaxis, stomach and uterine bleeding. After undergoing hematoma drainage, she was unsuccessfully treated with platelets, red blood cells, plasma cryoprecipitate transfusions, and antibiotics. Necropsy disclosed gastric ring-signet adenocarcinoma invading the serous layer, with massive disseminated intravascular coagulation and systemic neoplastic embolism. Multiple old and recent hyaline (rich in fibrin and platelets) microthrombi, and tumor emboli were observed in the bone marrow, meninges, liver, lungs, kidneys, lymph nodes, adrenals, thyroid, heart, pancreas, and ovaries (Krukenberg tumor).




How to Cite

Santos, V. M. dos, Rodrigues, D. B. R., Castro, E. C. da C., Saldanha, J. C., Soares, S., Teixeira, V. de P. A., & Reis, M. A. dos. (2001). Widespread hematogenous metastases and Trousseau’s syndrome in gastric adenocarcinoma . Revista Do Hospital Das Clínicas, 56(3), 91-96. https://doi.org/10.1590/S0041-87812001000300005



Case Report