Necrolytic migratory erythema associated with glucagonoma syndrome: a case report
Keywords:Necrolytic migratory erythema, Glucagonoma syndrome, Glucagonoma
AbstractNecrolytic migratory erythema is a rare skin condition that consists of migrating areas of erythema with blisters that heal with hyperpigmentation. It usually occurs in patients with an alpha islet cell tumor of the pancreas-or glucagonoma-and when associated with glucose intolerance, anemia, hyperglucagonemia, and weight loss defines the glucagonoma syndrome. We describe a 52-year-old female patient with necrolytic migratory erythema associated with glucagonoma syndrome who had metastatic disease at presentation and passed away one week after her admission. The autopsy showed a tumor in the body of the pancreas, which was diagnosed as a neuroendocrine tumor and confirmed by immunohistochemistry. The diagnosis of necrolytic migratory erythema is a matter of great importance, since it might be an auxiliary tool for the early detection of glucagonoma.
How to Cite
Dal Coleto, C. C., Mello, A. P. F. de, Piquero-Casals, J., Lima, F. R., Vilela, M. A. C., Festa-Neto, C., & Sanches Jr., J. A. (2001). Necrolytic migratory erythema associated with glucagonoma syndrome: a case report . Revista Do Hospital Das Clínicas, 56(6), 183-188. https://doi.org/10.1590/S0041-87812001000600005