Thrombotic thrombocytopenic purpura associated with dengue and chikungunya virus coinfection

case report during an epidemic period

Authors

  • Maria Luiza Almeida Bastos Universidade de Fortaleza
  • Ruth Maria Oliveira de Araújo Universidade Federal do Ceará, Faculdade de Medicina
  • Deivide de Sousa Oliveira Universidade Federal do Ceará, Faculdade de Medicina
  • Ana Nery Melo Cavalcante Universidade de Fortaleza
  • Geraldo Bezerra da Silva Junior Universidade de Fortaleza

Keywords:

Chikungunya virus, Dengue virus, Coinfection, Thrombotic thrombocytopenic purpur

Abstract

The present report shows the occurrence of thrombotic thrombocytopenic purpura (TTP) associated with acute dengue and chikungunya virus coinfection, manifesting as a severe disease with high mortality potential. The patient was a 28 year-old man with clinical and epidemiological diagnosis of arboviruses infections who developed thrombocytopenia and anemia, after which oral corticosteroid therapy was started. On the third day of hospitalization, he showed neurological alterations that simulated a cerebral vascular accident, but the imaging examination did not identify ischemic or hemorrhagic alterations. At that moment, the TTP hypothesis was raised so that plasmapheresis and corticosteroid pulse therapy were started, have been essential for the favorable evolution of the case.

Downloads

Download data is not yet available.

Downloads

Published

2018-11-09

Issue

Vol. 60 (2018)

Section

Case Report

How to Cite

Bastos, M. L. A., Araújo, R. M. O. de, Oliveira, D. de S., Cavalcante, A. N. M., & Silva Junior, G. B. da. (2018). Thrombotic thrombocytopenic purpura associated with dengue and chikungunya virus coinfection: case report during an epidemic period. Revista Do Instituto De Medicina Tropical De São Paulo, 60, e48. https://www.revistas.usp.br/rimtsp/article/view/151670