Adverse effect of the intermittent use of rifampin tor leprosy treatment

Authors

  • Priscila Maria de Oliveira Papaiordanou UNICAMP; Faculdade de Ciências Médicas
  • Maria Luiza Moretti Branchini UNICAMP; Faculdade de Ciências Médicas
  • Fernando Lopes Gonçales Júnior UNICAMP; Faculdade de Ciências Médicas
  • Francisco Hideo Aoki UNICAMP; Faculdade de Ciências Médicas
  • Raquel Silveira Bello Stucchi Boccato UNICAMP; Faculdade de Ciências Médicas
  • Marcelo de Carvalho Ramos UNICAMP; Faculdade de Ciências Médicas
  • Rogério de Jesus Pedro UNICAMP; Faculdade de Ciências Médicas

Keywords:

Insuficiência renal aguda, Hemólise aguda, Trombocitopenia, Hanseníase

Abstract

The authors present a case of acute renal failure, acute hemolysis and thrombocytopenia due to intermittent use of Rifampin for leprosy. These adverse reactions have rarely been discribed in the medical literature. During follow up there was recovery of renal function and complete remission of the hematological alterations. To our knowledge, this has been the first report of such adverse effects of Rifampin during leprosy therapy in Brazil. Pathogenetic aspects are discussed and current literature is reviewed.

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Published

1988-10-01

Issue

Vol. 30 No. 5 (1988)

Section

Therapeutic Assays

How to Cite

Papaiordanou, P. M. de O., Branchini, M. L. M., Gonçales Júnior, F. L., Aoki, F. H., Boccato, R. S. B. S., Ramos, M. de C., & Pedro, R. de J. (1988). Adverse effect of the intermittent use of rifampin tor leprosy treatment . Revista Do Instituto De Medicina Tropical De São Paulo, 30(5), 383-386. https://www.revistas.usp.br/rimtsp/article/view/28613