Differences in the antigenic profile of bloodstream and cell culture derived trypomastigotes of Trypanosoma cruzi

Authors

  • Ana M. M. Da Silva Instituto Butantan; Centro de Pesquisa e Formação em Imunologia da OMS/OPS
  • Cláudia I. Brodskyn Instituto Butantan; Centro de Pesquisa e Formação em Imunologia da OMS/OPS
  • Harumi A. Takehara Instituto Butantan; Centro de Pesquisa e Formação em Imunologia da OMS/OPS
  • I. Mota Instituto Butantan; Centro de Pesquisa e Formação em Imunologia da OMS/OPS

Keywords:

Trypanosoma cruzi, T. cruzi antigens, Trypomastigotes

Abstract

A comparative study of the antigenic profile of bloodstream and cell culture derived trypomastigotes showed many differences in their components. Using mouse anti-T. cruzi antibodies the differences were located mostly in the 120 kDa band, whereas using chagasic patient sera the differences were located in the 85 and 52 kDa bands. These findings might explain known physiological differences between trypomatigotes obtained from cell culture and from infected blood. A brief report of this work has already been published9.

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Published

1989-06-01

Issue

Vol. 31 No. 3 (1989)

Section

Original Articles

How to Cite

Silva, A. M. M. D., Brodskyn, C. I., Takehara, H. A., & Mota, I. (1989). Differences in the antigenic profile of bloodstream and cell culture derived trypomastigotes of Trypanosoma cruzi . Revista Do Instituto De Medicina Tropical De São Paulo, 31(3), 146-150. https://www.revistas.usp.br/rimtsp/article/view/28655