Serologic efficacy of a two dose measles vaccination schedule at 6 and 11 months of age: a prospective study
Keywords:
Sarampo, VacinaçãoAbstract
A prospective study was designed to evaluate the serologic efficacy of a two dose meas les vaccination schedule, at 6 months and 11 months of age. Infants were given a further attenuated measles virus vaccine (BIKEN CAM 70, Fundação Oswaldo Cruz) and serum samples were tested for measles antibodies using the indirect immunofluorescence technique (IFA) and ELISA. Seroconversion rates 6 to 12 months (mean of 8.0 ±1.7 months) following the second dose of measles vaccine were 88.5% (85/96) by IFA and 96.8% (93/96) by ELISA. No measles cases were reported during the study period. In regions where a significant proportion of measles cases occurs before nine months of age, vaccination with a two doses schedule, at 6 and 11 months of age, may represent an alternative for measles control.Downloads
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Published
1990-12-01
Issue
Section
Serology
How to Cite
Pannuti, C. S., Souza, V. A. U. F. de, Sato, H. K., Fink, M. C. D. S., Ribeiro, M. I., Hisi, S. K., Castelo, A., & Mendonça, J. S. de. (1990). Serologic efficacy of a two dose measles vaccination schedule at 6 and 11 months of age: a prospective study . Revista Do Instituto De Medicina Tropical De São Paulo, 32(6), 450-455. https://www.revistas.usp.br/rimtsp/article/view/28777