Diagnosis of Helicobacter pylori: comparison of an urease test, histological visualization of curved bacteria and culture
Keywords:
Campylobacter pylori, Helicobacter pylori, Diagnostic, Technical assay, Campylobacter-like organisms, Urease testAbstract
Helicobacter pylori was investigated in 189 patients for culture, microscopic visualization of campylobacter-like organisms (CLO) and a ten minute urease test. In 136 (72%) the bacteria was isolated, and in 98 of them CLO were histologically detected. Specificity, sensitivity, positive and negative predictive values of microscopic visualization of CLO were: 0.77, 0.73, 0.97 and 0.51, respectively; 98 culture-positive patients were urease test positive. Specificity, sensitivity, positive and negative predictive values of the urease test were: 0.83, 0.72, 0.92 and 0.54, respectively. Comparing the urease test with culture of H. pylori combined with microscopic visualization of CLO, its specificity, sensitivity, positive and negative predictive values were: 0.95, 0.71, 0.98 and 0.48, respectively. Probably, these values are not real, since bacteria different from H. pylori could be misclassified as CLO.Downloads
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Published
1991-02-01
Issue
Section
Brief Communication
How to Cite
Hernández, F., Rivera, P., Sigarán, M., & Miranda, J. (1991). Diagnosis of Helicobacter pylori: comparison of an urease test, histological visualization of curved bacteria and culture . Revista Do Instituto De Medicina Tropical De São Paulo, 33(1), 80-82. https://www.revistas.usp.br/rimtsp/article/view/28797