Immunomodulatory effect of glucan on the response to experimental antirabies vaccination

Authors

  • Milene S. Tino Escola Paulista de Medicina; Disciplina de Imunologia
  • Maria L. Carrieri Instituto Pasteur
  • Carlos R Zanetti Instituto Pasteur
  • Nelson F. Mendes Escola Paulista de Medicina; Disciplina de Imunologia
  • Octavio A.C. Pereira Instituto Pasteur

Keywords:

Glucan, Antirabies vaccination, Rabies

Abstract

The objective of lhe present study was to determine the stimulatory response to antirabies vaccination promoted by glucan in mice. Glucan increased both resistance to infection and antibody titres and this effect was more evident when glucan was used at dose of 0.5 mg, administered intraperitoneally before, during and after immunization and when the challenge virus was applied to the foot-pad.

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Published

1993-10-01

Issue

Vol. 35 No. 5 (1993)

Section

Immunology

How to Cite

Tino, M. S., Carrieri, M. L., Zanetti, C. R., Mendes, N. F., & Pereira, O. A. (1993). Immunomodulatory effect of glucan on the response to experimental antirabies vaccination . Revista Do Instituto De Medicina Tropical De São Paulo, 35(5), 431-435. https://www.revistas.usp.br/rimtsp/article/view/29081