Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects

Authors

  • C.L.P. Lancellotti Faculty of Medical Science of Santa Casa of São Paulo; Inst. Infect. of Emilio Ribas
  • C.E.P. Corbett Univ. of São Paulo Medical School; Lab. Path. Infect. Dis
  • M.I.S. Duarte Univ. of São Paulo Medical School; Lab. Path. Infect. Dis

Keywords:

Measles, Virus, Central Nervous System, Pathology, Ultrastructure, Pathogenesis

Abstract

Histopathological and ultrastructural studies of 23 patients who died with clinical diagnosis of measles were carried out. In 12 cases viral nucleocapsids were searched by electron microscopy and detected in 100% of the cases in the lungs and in 50% of the cases in the central nervous system. They were mostly intranuclear. Histopathological changes associated to neurological alterations and the detection of virion are discussed in relation to acute and delayed clinical manifestations.

Downloads

Download data is not yet available.

Downloads

Published

1995-04-01

Issue

Vol. 37 No. 2 (1995)

Section

Virology

How to Cite

Lancellotti, C., Corbett, C., & Duarte, M. (1995). Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects . Revista Do Instituto De Medicina Tropical De São Paulo, 37(2), 137-143. https://www.revistas.usp.br/rimtsp/article/view/29249