Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes

Authors

  • Claudia de Oliveira e SILVA Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública
  • Marli da Silva Pereira AZEVEDO Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública
  • Célia Maria de Almeida SOARES Universidade Federal de Goiás; Laboratório de Biologia Molecular
  • Regina Maria Bringel MARTINS Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública
  • Carmen Helena RAMOS Laboratório Central de Saúde Pública Dr. Giovanni Cysneiros
  • Roberto Ruhman DAHER Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública
  • Divina das Dôres de Paula CARDOSO Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública

Keywords:

Hepatitis B, HBV-DNA, Subtypes

Abstract

The presence of serological markers for hepatitis B virus (HBsAg, anti-HBc IgM and Anti-HBc total) was investigated in the serum of 1,396 individuals who had clinical suspect of hepatitis. It was observed that 50.7% of the individuals were positive and, from the total of the studied individuals, 14.5% were positive for HBsAg. From these, 8.5% were also positive for anti-HBc IgM. The analysis in relation to gender showed a higher seroprevalence index among male individuals (p < 0.0001). It was observed the occurrence of subtypes adw2 (62.7%), ayw3 (23.5%), ayw2 (9.8%) and adw4 (3.9%). The viral DNA was detected in 61 (33.9%) HBsAg positive samples and in one sample positive only for anti-HBc total. These results indicate an important incidence of the HBV infection in this population, and reinforce previous studies regarding this virus in the central west region of Brazil.

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Published

2002-12-01

Issue

Section

Hepatitis

How to Cite

Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes . (2002). Revista Do Instituto De Medicina Tropical De São Paulo, 44(6), 331-334. https://www.revistas.usp.br/rimtsp/article/view/30655