Histoplasma capsulatum fungemia in patients with acquired immunodeficiency syndrome: detection by lysis-centrifugation blood-culturing technique

Authors

  • Flávio de Mattos Oliveira Universidade Federal do Rio Grande do Sul; Hospital Santa Rita, Santa Casa-Complexo Hospitalar,; Laboratório de Micologia
  • Sérgio Sônego Fernandes UFRGS; Faculdade de Medicina
  • Cecília Bittencourt Severo UFRGS; Faculdade de Medicina
  • Luciana Silva Guazzelli Universidade Federal do Rio Grande do Sul; Hospital Santa Rita, Santa Casa-Complexo Hospitalar,; Laboratório de Micologia
  • Luiz Carlos Severo UFRGS; Departamento de Medicina Interna

Keywords:

Histoplasma capsulatum, Histoplasmosis, Lysis-centrifugation, Fungemia

Abstract

Progressive disseminated histoplasmosis (PDH) is an increasingly common cause of infection in patients with acquired immune deficiency syndrome (AIDS). We report 21 cases of PDH associated with AIDS diagnosed by lysis-centrifugation blood culture method. The most prevalent clinical findings were fever, weight loss, respiratory symptoms, and mucocutaneous lesions. Chest roentgenogram showed diffuse pulmonary infiltrates in 13 of 21 patients (62%). Brochoalveolar fluid has yelded positive culture in four patients only in medium with cycloheximide.

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Published

2007-06-01

Issue

Vol. 49 No. 3 (2007)

Section

Mycology

How to Cite

Oliveira, F. de M., Fernandes, S. S., Severo, C. B., Guazzelli, L. S., & Severo, L. C. (2007). Histoplasma capsulatum fungemia in patients with acquired immunodeficiency syndrome: detection by lysis-centrifugation blood-culturing technique . Revista Do Instituto De Medicina Tropical De São Paulo, 49(3), 135-138. https://www.revistas.usp.br/rimtsp/article/view/31079