FIRST REPORT ON OTOTOXICITY OF MEGLUMINE ANTIMONIATE
Abstract
Introduction: Pentavalent antimonials are the first drug of choice in the treatment of tegumentary leishmaniasis. Data on ototoxicity related with such drugs is scarcely available in literature, leading us to develop a study on cochleovestibular functions. Case Report: A case of a tegumentary leishmaniasis patient, a 78-year-old man who presented a substantial increase in auditory threshold with tinnitus and severe rotatory dizziness during the treatment with meglumine antimoniate, is reported. These symptoms worsened in two weeks after treatment was interrupted. Conclusion: Dizziness and tinnitus had already been related to meglumine antimoniate. However, this is the first well documented case of cochlear-vestibular toxicity related to meglumine antimoniate.Downloads
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Published
2014-09-01
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Section
Case Report
How to Cite
Valete-Rosalino, C. M., Araujo-Melo, M. H., Bezerra, D. C. de O., Barcelos, R. O. de, Melo-Ferreira, V. de, Torraca, T. S. de S., Martins, A. C. da C., Moreira, J. S., Vargas, M. C. M., Braga, F. P. B., Salgueiro, M. de M., Saheki, M. N., & Schubach, A. O. (2014). FIRST REPORT ON OTOTOXICITY OF MEGLUMINE ANTIMONIATE . Revista Do Instituto De Medicina Tropical De São Paulo, 56(5), 439-442. https://www.revistas.usp.br/rimtsp/article/view/87540