Abordagens terapêuticas do Condiloma Acuminado em crianças e adolescentes

Autores

DOI:

https://doi.org/10.11606/issn.2176-7262.rmrp.2022.195167

Palavras-chave:

Condiloma Acuminado, Infecções por Papillomavirus, Imiquimode

Resumo

Objetivos: A infecção pelo papiloma vírus humano dos tipos 6 e 11 pode evoluir para Condiloma Acuminado. Sua transmissão é principalmente via sexual, de forma que a presença dessas verrugas em crianças deve ser considerada sinal de alarme para investigação de abuso. Eventualmente, contudo, ocorre por autoinoculação ou fômites. O tratamento é desafiador, dado que apesar do extenso arsenal, a recorrência se faz comum. A presente revisão sistemática advém a comparar taxas de sucesso das estratégias terapêuticas, objetivando fornecer substrato para escolha acertada no tratamento da doença em crianças e adolescentes. Métodos: Foi realizada Revisão sistemática baseada no guideline Preferred Report Items for Systematic Reviews and Meta-Analyses (PRISMA), registrada na Plataforma PROSPERO sob identificação CRD42021262090. Resultados: 211 estudos foram encontrados nas databases consultadas, de forma que 30 atenderam as propostas de critérios estabelecidos na pesquisa sistematizada. Esses passaram extração de dados para síntese qualitativa, demonstrando eficácia de métodos não-invasivos a invasivos.  Conclusões: Mediante bons resultados em resolução da doença e reduzidos efeitos adversos, a terapia mais popular entre os autores foi o Imiquimode. A pesquisa chamou atenção à necessidade de estudos mais robustos e metodologias mais complexas a cerca das abordagens terapêuticas do Condiloma Acuminado em crianças e adolescentes.

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Biografia do Autor

Denise Gasparetti Drumond, Universidade Federal de Juiz de Fora, Juiz de Fora, (MG) Brasil

Docente Associada

Bárbara Bizzo Castelo, Universidade Federal de Juiz de Fora, Juiz de Fora, (MG) Brasil

Acadêmica do Curso de Graduação em Medicina

Samuel Drumond Esperança, Hospital Israelita Albert Einstein, São Paulo, (SP), Brasil

Médico residente

Fellipe Bruno Dominiquini, Universidade Federal de Juiz de Fora, Juiz de Fora, (MG) Brasil

Médico residente

Neila Maria de Góis Speck, Universidade Federal de São Paulo, São Paulo, (SP), Brasil

Doutora

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Publicado

2022-12-27

Como Citar

1.
Drumond DG, Castelo BB, Esperança SD, Dominiquini FB, Speck NM de G. Abordagens terapêuticas do Condiloma Acuminado em crianças e adolescentes. Medicina (Ribeirão Preto) [Internet]. 27 de dezembro de 2022 [citado 24 de fevereiro de 2024];55(4):e-195167. Disponível em: https://www.revistas.usp.br/rmrp/article/view/195167

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