Potentially inappropriate prescribing in older adults in Mexico
DOI:
https://doi.org/10.11606/s1518-8787.20210550033110Keywords:
Old person, Inappropriate Prescribing, Comorbidity, Misuse of Prescription Drugs, Medication-Related Side Effects and Adverse ReactionsAbstract
OBJETIVE: To identify and quantify potentially inappropriate prescribing (prescripción potencialmente inapropiada, PPI) and other drug prescribing problems in public health care services in a population-based study at the three existing levels of complexity in Mexico.
METHODSDescriptive analysis of the Study on Satisfaction of Users of the Social Protection System in Health 2014–2016, prescription and drug supply section, to obtain the prevalence of PPI in older adults (≥ 65 years), based on Beers, STOPP, Prescrire and BSP listings using AM (older adults) prescription indicators, one for each listing.
RESULTSMost older adults (67%) were prescribed at least one medication, with a mean of 2.7 medications per prescription. The PPI prevalence was 74% according to the BSP criteria, 67% according to the STOPP listing, 59% with the Beer criteria, and 20% with Prescrire. The most frequent PPI prescriptions were NSAIDs, vasodilators and sulfonylureas.
CONCLUSIONSThe use of PPIs in AM is high in Mexico. The higher prevalence found in this study may reflect the use of a source with population representativeness. The partial use and adaptations of the criteria make difficult comparing the studies; however, the STOPP criteria are the ones with the highest prevalence, as they cover a greater number of drugs and their use is more common in the first level of care.
References
Hill-Taylor B, Sketris I, Hayden J, Byrne S, O’Sullivan D, Christie R. Application of the STOPP/START criteria: a systematic review of the prevalence of potentially inappropriate prescribing in older adults, and evidence of clinical, humanistic and economic impact. J Clin Pharm Ther. 2013;38(5):360-72. https://doi.org/10.1111/jcpt.12059
Fick DM, Mion LC, Beers MH, Waller JL. Health outcomes associated with potentially inappropriate medication use in older adults. Res Nurs Health. 2008;31(1):42-51. https://doi.org/10.1002/nur.20232
Gnjidic D, Le Couteur DG, Pearson SA, McLachlan AJ, Viney R, Hilmer SN, et al. High risk prescribing in older adults: prevalence, clinical and economic implications and potential for intervention at the population level. BMC Public Health. 2013;13(1):115. https://doi.org/10.1186/1471-2458-13-115
Rankin A, Cadogan CA, Patterson SM, Kerse N, Cardwell CR, Bradley MC, et al. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev. 2018;9(9):CD008165 https://10.1002/14651858.CD008165.pub4
Cahir C, Fahey T, Teeling M, Teljeur C, Feely J, Bennett K. Potentially inappropriate prescribing and cost outcomes for older people: a national population study. Br J Clin Pharmacol. 2010;69(5):543-52. https://doi.org/10.1111/j.1365-2125.2010.03628.x
Corona-Rojo JA, Altagracia-Martínez M, Kravzov-Jinich J, Vázquez-Cervantes L, Pérez-Montoya E, Rubio-Poo C. Potential prescription patterns and errors in elderly adult patients attending public primary health care centers in Mexico City. Clin Interv Aging. 2009;4:343-50. https://doi.org/10.2147/cia.s5198
Miller GE, Sarpong EM, Davidoff AJ, Yang EY, Brandt NJ, Fick DM. Determinants of potentially inappropriate medication use among community-dwelling older adults. Health Serv Res. 2017;52(4):1534-49. https://doi.org/10.1111/1475-6773.12562
American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2012;60(4):616-31. https://doi.org/10.1111/j.1532-5415.2012.03923.x
Gallagher P, O’Mahony D. STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers’ criteria. Age Ageing. 2008;37(6):673-9. https://doi.org/10.1093/ageing/afn197
Towards better patient care: drugs to avoid in 2016. Prescrire Int. 2016;25(170):105-11.
Secretaría de Salud (MX), Dirección General de Información en Salud. Cubos dinámicos de información, proyecciones de población en México 1990-2030, CONAPO. Ciudad de México; 2020
Secretaría de Salud (MX), Dirección General de Información en Salud. Cubos dinámicos de información, defunciones. Ciudad de México; 2020
Martínez-Arroyo JL, Gómez-García A, Sauceda-Martinez D. Prevalencia de la polifarmacia y la prescripción de medicamentos inapropiados en el adulto mayor hospitalizado por enfermedades cardiovasculares. Gac Med Mex. 2014;150 Supl 1:29-38.
World Health Organization. eEML - Electronic Essential Medicines List [citado 22 Jul 2020]. Geneva (CH): WHO; 2020. Disponible en: https://list.essentialmeds.org/
Zavala Rubio JD, Terán Martínez MA, Nava Álvarez MG, Pineda Maldonado ML, Mata Márquez MJ. Detección de polifarmacia y prescripción potencialmente inapropiada en el adulto mayor en una unidad de medicina familiar. Aten Fam. 2018;25(4):141-5. https://doi.org/10.22201/facmed.14058871p.2018.4.67257
Baza-Chavarría B, Martínez-Peña A, Alvarado-Gutiérrez T. Prescripción farmacológica inapropiada en adultos mayores con síndrome metabólico en la unidad de medicina familiar no. 31. Aten Fam. 1 de julio de 2017; 24(3):97-101. https://doi.org/10.1016/j.af.2017.07.002
Secretaría de Salud (MEX), Comisión Nacional de Protección Social en Salud; Instituto Nacional de Salud Pública. Estudio de Satisfacción de Usuarios del Sistema de Protección Social en Salud 2015. Ciudad de México: CNPSS; 2015.
U.S. Food and Drug Administration. Information by drug class. Silver Spring, MD; 2020 [citado 24 jun 2020]. Disponible en: https://www.fda.gov/drugs/drug-safety-and-availability/information-drug-class
Organización Panamericana de la Salud. La salud de los adultos mayores: una visión compartida. Washington, DC: OPS; 2011. Disponible en: https://iris.paho.org/handle/10665.2/51598
Delgado Silveira E, Montero Errasquín B, Muñoz García M, Vélez-Díaz-Pallarés M, Lozano Montoya I, Sánchez-Castellano C, et al. Mejorando la prescripción de medicamentos en las personas mayores: una nueva edición de los criterios STOPP-START. Rev Esp Geriatría Gerontol. 2015;50(2):89-96. https://doi.org/10.1016/j.regg.2014.10.005
Galvin R, Moriarty F, Cousins G, Cahir C, Motterlini N, Bradley M, et al. Prevalence of potentially inappropriate prescribing and prescribing omissions in older Irish adults: findings from The Irish LongituDinal Study on Ageing study (TILDA). Eur J Clin Pharmacol. 2014;70(5):599-606. https://doi.org/10.1007/s00228-014-1651-8
Chiapella L, Montemarani Menna J, Marzi M. Medicamentos potencialmente inapropiados en adultos mayores de la ciudad de Rosario, Argentina. En: 26. Jornadas de Jóvenes Investigadores AUGM; 17-19 oct 2018 [citado 24 jun 2020]; Mendoza, Argentina. Disponible en: https://bdigital.uncu.edu.ar/fichas.php?idobjeto=13091
Casas-Vásquez P, Ortiz-Saavedra P, Penny-Montenegro E. Estrategias para optimizar el manejo farmacológico en el adulto mayor. Rev Peru Med Exp Salud Pública. 2016;33(2):335. https://doi.org/10.17843/rpmesp.2016.332.2153
Bao Y, Shao H, Bishop TF, Schackman BR, Bruce ML. Inappropriate medication in a national sample of US elderly patients receiving home health care. J Gen Intern Med. 2012;27(3):304-10. https://doi.org/10.1007/s11606-011-1905-4
Goulding MR. Inappropriate medication prescribing for elderly ambulatory care patients. Arch Intern Med. 2004;164(3):305-12. https://doi.org/10.1001/archinte.164.3.305
Carrier H, Zaytseva A, Bocquier A, Villani P, Verdoux H, Fortin M, et al. GPs’ management of polypharmacy and therapeutic dilemma in patients with multimorbidity: a cross-sectional survey of GPs in France. Br J Gen Pract. 2019;69(681):e270-8. https://doi.org/10.3399/bjgp19X701801
Javier de Andrés A, Acuña B JB , Alicia Olivares S. Dolor en el paciente de la tercera edad. Rev Med Clin Las Condes. 2014;25(4):674-86. https://doi.org/10.1016/S0716-8640(14)70089-6
Secretaría de Salud (MX), Consejo de Salubridad General. Cuadro básico y catálogo de medicamentos. Edición 2016. Ciudad de México; 2016 [citado 1 jul 2020]. Disponible en: http://www.csg.gob.mx/descargas/pdf/priorizacion/cuadro-basico/med/catalogo/2016/EDICION_2016_MEDICAMENTOS.pdf
Salech F, Daniel Palma QF, Pablo Garrido QF. Epidemiología del uso de medicamentos en el adulto mayor. Rev Med Clin Las Condes. 2016;27(5):660-70. https://doi.org/10.1016/j.rmclc.2016.09.011
Secretaría de Salud (MX). Tratamiento de la Diabetes Mellitus tipo 2 en el primer nivel de atención. Ciudad de México: CENETEC-Salud; 2018. Disponible en: http://www.cenetec.salud.gob.mx/descargas/gpc/CatalogoMaestro/718_GPC_Tratamiento_de_diabetes_mellitus_tipo_2_/718GER.pdf
Organización Mundial de la Salud. Informe Mundial sobre el Envejecimiento y la Salud. Ginebra (CH): OMS; 2015. (Informe Nº WHO/FWC/ALC/15.01). Disponible en: https://www.who.int/ageing/publications/world-report-2015/es/
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Copyright (c) 2021 Pedro Jesús Saturno-Hernández, Ofelia Poblano-Verástegui, Omar Acosta-Ruiz, Arturo Cuauhtémoc Bautista-Morales, Patricia María Gómez-Cortez, José Luis Alcántara-Zamora, Luis Miguel Gutiérrez-Robledo
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