The evolution of immunoglobulins involved in the immune response to mice infected with Schistosoma mansoni
DOI:
https://doi.org/10.1590/S0034-89101984000200006Keywords:
Schistosoma mansoni, Immunoglobulins, SchistosomiasisAbstract
The evolution of immunoglobulins involved in the immune response of mice infected with Schistosoma mansoni was studied by using plurispecific sera and the bi-dimensional immunoelectrophoresis technique. Determinations of the level of different immunoglobulins in infected animals and control groups which were mantained under similar conditions detected significant variations in both groups over the 8 weeks of observation. The study of the relationship (I/C) between the level of immunoglobulins of the infected animals (I) and that of corresponding control (C) showed that the infected animals presented a primary response (1-2 weeks after infection date) and a secondary response that was initiated in the 6th week of infection, with levels of IgA, IgG and IgM that were respectively 4.5, 3 and 2 times higher than those of corresponding control.Downloads
Published
1984-04-01
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Section
Original Articles
How to Cite
The evolution of immunoglobulins involved in the immune response to mice infected with Schistosoma mansoni . (1984). Revista De Saúde Pública, 18(2), 138-154. https://doi.org/10.1590/S0034-89101984000200006