Malaria transmission model for different levels of acquired immunity and temperature-dependent parameters (vector)
DOI:
https://doi.org/10.1590/S0034-89102000000300003Keywords:
Malaria transmission, Epidemiologic models, Anopheles^i1^sparasitol, Plasmodium^i1^sphysiol, Host parasitic relations, Insect vectorsAbstract
OBJECTIVE: Describe the overall transmission of malaria through a compartmental model, considering the human host and mosquito vector. METHODS: A mathematical model was developed based on the following parameters: human host immunity, assuming the existence of acquired immunity and immunological memory, which boosts the protective response upon reinfection; mosquito vector, taking into account that the average period of development from egg to adult mosquito and the extrinsic incubation period of parasites (transformation of infected but non-infectious mosquitoes into infectious mosquitoes) are dependent on the ambient temperature. RESULTS: The steady state equilibrium values obtained with the model allowed the calculation of the basic reproduction ratio in terms of the model's parameters. CONCLUSIONS: The model allowed the calculation of the basic reproduction ratio, one of the most important epidemiological variables.Downloads
Published
2000-06-01
Issue
Section
Original Articles
How to Cite
Yang, H. M. (2000). Malaria transmission model for different levels of acquired immunity and temperature-dependent parameters (vector) . Revista De Saúde Pública, 34(3), 223-231. https://doi.org/10.1590/S0034-89102000000300003