Hetacillin in a single dose in the treatment of gonorrhoeae

Abstract

Schemes of treatment with one single parenteral injection or single oral dosis of a broad spectrum antibiotic - Hetacillin - has been employed in 155 patients with acute gonorrhoeae who were, then, followed-up during 15 days in the Service of VD of the School of Public Health, University of São Paulo. The diagnosis and control of the cases were performed through smears and cultures of the urethral discharge. Cure has been attained in 88,6% of 70 patients treated with 3.0 g of Hetacillin by oral route, in a single dosis, and in 93% of 85 patients treated with one single intramuscular injection of Hetacillin (1.0 g). Discharge has disappeared in an average of 48 hours in both schedules of treatment. No side effects or toxicity were observed.