Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil

Authors

  • Ligia G Fedeli Universidade de Sao Paulo; Hospital Universitario; Laboratorio Clinico
  • Pedro G Vidigal Universidade Federal de Minas Gerais; Faculdade de Medicina; Departamento de Propedeutica Complementar
  • Claudia Mendes Leite Universidade Federal do Espirito Santo; Centro de Ciencias da Saude; Departamento de Ciencias Fisiologicas
  • Cristina D Castilhos Universidade Federal do Rio Grande do Sul; Departamento de Medicina Social; Programa de Pos-Graduacao em Epidemiologia
  • Robercia Anjos Pimentel Universidade Federal da Bahia; Instituto de Ciencias da Saude
  • Viviane C Maniero Fundacao Oswaldo Cruz; Escola Nacional de Saude Publica; Departamento de Epidemiologia e Metodos Quantitativos em Saude
  • Jose Geraldo Mill Universidade Federal do Rio Grande do Sul; Departamento de Medicina Social; Programa de Pos-Graduacao em Epidemiologia
  • Paulo A Lotufo Universidade do Estado de Sao Paulo; Faculdade de Medicina; Laboratorio de Genetica e Cardiologia Molecular; Instituto do Coracao
  • Alexandre C Pereira Universidade do Estado de Sao Paulo; Faculdade de Medicina; Laboratorio de Genetica e Cardiologia Molecular; Instituto do Coracao
  • Isabela M Bensenor Universidade de Sao Paulo; Hospital Universitario; Centro de Pesquisa Clinica e Epidemiologica

DOI:

https://doi.org/10.1590/rsp.v47isuppl.2.76736

Abstract

The ELSA (Estudo Longitudinal de Saúde do Adulto - Brazilian Longitudinal Study for Adult Health) is a multicenter cohort study which aims at the identification of risk factors associated with type 2 diabetes and cardiovascular diseases in the Brazilian population. The paper describes the strategies for the collection, processing, transportation, and quality control of blood and urine tests in the ELSA. The study decided to centralize the tests at one single laboratory. The processing of the samples was performed at the local laboratories, reducing the weight of the material to be transported, and diminishing the costs of transportation to the central laboratory at the Universidade de São Paulo Hospital. The study included tests for the evaluation of diabetes, insulin resistance, dyslipidemia, electrolyte abnormalities, thyroid hormones, uric acid, hepatic enzyme abnormalities, inflammation, and total blood cell count. In addition, leukocyte DNA, urine, plasma and serum samples were stored. The central laboratory performed approximately 375,000 tests.

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Published

2013-06-01

Issue

Vol. 47 No. suppl. 2 (2013)

Section

Articles

How to Cite

Fedeli, L. G., Vidigal, P. G., Leite, C. M., Castilhos, C. D., Pimentel, R. A., Maniero, V. C., Mill, J. G., Lotufo, P. A., Pereira, A. C., & Bensenor, I. M. (2013). Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil. Revista De Saúde Pública, 47(suppl. 2), 63-71. https://doi.org/10.1590/rsp.v47isuppl.2.76736