Intrapopulation fixation index dynamics in finite populations with variable outcrossing rates

Abstract

The intrapopulation fixation index ( f ) is inversely related to the outcrossing rate (t). Results obtained from data on molecular markers of natural populations have shown that these values are highly variable, even when measured in the same group of individuals. It is thus suggested that factors besides those described in Wright's genetic equilibrium must be operating. Using simulated data sets this study shows that the finite size condition of a population is sufficient to spread the estimated f values along a range at equilibrium, as opposed to keeping them at the theoretical equilibrium point. The variation in outcrossing rates can amplify this range considerably. Correlation between estimated f values obtained from different loci in this condition showed to be negatively related to the outcrossing rates, and positively related to the variance of these rates along generations. The finite size of populations associated to small fluctuations in t mean values over time may explain the usually reported high variation among estimated f values of different loci.