Myelolipoma of the posterior mediastinum in a patient with chronic dyserythropoietic anemia

Authors

  • Cristiano Claudino Oliveira Universidade Estadual Paulista. Botucatu School of Medicine. Department of Pathology
  • Gilmar Felisberto Junior Universidade Estadual Paulista. Botucatu School of Medicine. Department of Surgery and Orthopedics
  • Viviane Hellmeister Camolese Universidade Estadual Paulista. Botucatu School of Medicine. Department of Pathology
  • Erica Nishida Hasimoto Universidade Estadual Paulista. Botucatu School of Medicine. Department of Pathology
  • Daniele Cristina Cataneo Universidade Estadual Paulista. Botucatu School of Medicine. Department of Pathology
  • Antônio José Maria Cataneo Universidade Estadual Paulista. Botucatu School of Medicine. Department of Pathology
  • Julio De Faveri Universidade Estadual Paulista. Botucatu School of Medicine. Department of Pathology

DOI:

https://doi.org/10.4322/acr.2016.047

Keywords:

Myelolipoma, Mediastinal Neoplasms, Mediastinum, Anemia

Abstract

Myelolipoma (ML) is an uncommon benign mesenchymal neoplasia composed of mature adipose and hematopoietic tissues of uncertain etiology. Less than 3% of MLs occur in the mediastinal topography. The main differential diagnosis involves extramedullary hematopoiesis; therefore, pathological evaluation is essential for the definitive diagnosis. The authors report the case of a 50-year-old man diagnosed with congenital dyserythropoiesis and secondary hemosiderosis, who presented a posterior mediastinal tumor. The tumor was resected. It was macroscopically characterized by mature fat tissue with fibrous areas and soft consistency, which was yellowish at the cut surface. Histology revealed a well-defined nodule composed of adipocytes and hematopoietic tissue represented by erythroid, granulocytic, and megakaryocytic series, which was consistent with the diagnosis of ML located in the posterior mediastinum. There was no recurrence of the lesion during the 3-year follow-up. The aim of this report is to show the diagnosis of an unusual mediastinal lesion in the context of a chronic hematologic disease

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Published

2016-09-11

How to Cite

Oliveira, C. C., Felisberto Junior, G., Camolese, V. H., Hasimoto, E. N., Cataneo, D. C., Cataneo, A. J. M., & De Faveri, J. (2016). Myelolipoma of the posterior mediastinum in a patient with chronic dyserythropoietic anemia. Autopsy and Case Reports, 6(3), 35-39. https://doi.org/10.4322/acr.2016.047

Issue

Section

Article / Clinical Case Report