Balo’s concentric lesions with concurrent features of Schilder’s disease in relapsing multiple sclerosis: neuropathological findings
DOI:
https://doi.org/10.4322/acr.2016.058Keywords:
Multiple Sclerosis, Atypical Inflammatory Demyelination, Balo’s Concentric Sclerosis, Schilder’s Disease, PathologyAbstract
Atypical inflammatory demyelinating syndromes are rare neurological diseases that differ from multiple sclerosis (MS), owing to unusual clinicoradiological and pathological findings, and poor responses to treatment. The distinction between them and the criteria for their diagnoses are poorly defined due to the lack of advanced research studies. Balo’s concentric sclerosis (BCS) and Schilder’s disease (SD) are two of these syndromes and can present as monophasic or in association with chronic MS. Both variants are difficult to distinguish when they present in acute stages. We describe an autopsy case of middle-aged female with a chronic history of MS newly relapsed with atypical demyelinating lesions, which showed concurrent features of BCS and SD. We also describe the neuropathological findings, and discuss the overlapping features between these two variantsDownloads
Download data is not yet available.
Downloads
Published
2016-12-11
Issue
Section
Article / Autopsy Case Report
License
Copyright
Authors of articles published by Autopsy and Case Report retain the copyright of their work without restrictions, licensing it under the Creative Commons Attribution License - CC-BY, which allows articles to be re-used and re-distributed without restriction, as long as the original work is correctly cited.
How to Cite
Kurdi, M., & Ramsay, D. (2016). Balo’s concentric lesions with concurrent features of Schilder’s disease in relapsing multiple sclerosis: neuropathological findings. Autopsy and Case Reports, 6(4), 21-26. https://doi.org/10.4322/acr.2016.058