Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease

Authors

  • Arpitha Kollabathula Institute of Medical Education and Research, Department of Histopathology
  • Vikarn Vishwajeet Institute of Medical Education and Research, Department of Histopathology https://orcid.org/0000-0002-2927-2603
  • Kirti Gupta Institute of Medical Education and Research - Department of Histopathology https://orcid.org/0000-0002-9999-3203
  • Suvradeep Mitra Institute of Medical Education and Research, Department of Histopathology https://orcid.org/0000-0002-5520-8306
  • Vibhav Sharma Institute of Medical Education and Research, Department of Internal Medicine
  • Pallab Ray Institute of Medical Education and Research, Department of Medical Microbiology https://orcid.org/0000-0003-3369-2640
  • Ashish Bhalla Institute of Medical Education and Research, Department of Internal Medicine

DOI:

https://doi.org/10.4322/acr.2019.128

Keywords:

Brucellosis, Amyloidosis, Autopsy, Polycystic Kidney, Autosomal Dominant

Abstract

We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease.

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Published

2020-01-24

How to Cite

Kollabathula, A., Vishwajeet, V., Gupta, K., Mitra, S., Sharma, V., Ray, P., & Bhalla, A. (2020). Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease. Autopsy and Case Reports, 10(1), e2019128. https://doi.org/10.4322/acr.2019.128

Issue

Section

Article / Autopsy Case Report