La prevalencia de linfedema tras tratamiento de cáncer de mama en mujeres con sobrepeso
DOI:
https://doi.org/10.1590/1809-2950/15214123032016Resumen
El cáncer de mama es la neoplasia que más ocurre en el mundo, y el linfedema es una de las complicaciones más frecuentes de su tratamiento. El aumento del índice de masa corporal es uno de los factores de riesgo para el linfedema tras el tratamiento de cáncer de mama. El propósito de este estudio fue verificar la incidencia de linfedema en mujeres sometidas a mastectomía y que están con sobrepeso y obesidad. Los resultados mostraron que el riesgo de linfedema en mujeres con sobrepeso y obesidad ha sido cuatro veces mayor (Odds ratio, OR=3,887). Cuanto mayor es el índice de masa corporal, mayor es la probabilidad de linfedema, con aumento de riesgo de 40% para obesidad II.Descargas
Referencias
Dieli-Conwright CM, Mortimer JE, Schroeder ET, Courneya
K, Demark-Wahnefried W, Buchanan TA, et al. Randomized
controlled trial to evaluate the effects of combined
progressive exercise on metabolic syndrome in breast cancer
survivors: rationale, design, and methods. BMC Cancer.
;14(238):1-12.
Instituto Nacional de Câncer. Estimativa 2016: incidência de
câncer no Brasil. Rio de Janeiro: INCA; 2016.
Kulie T, Slattengren A, Redmer J, Counts H, Eglasb A, Schrager
S. Obesity and women’s health: an evidence – based review. J
Am Board Fam Med. 2011;24(1):75-85.
DeSantis C, Siegel R, Bandi P, Jemal A. Breast cancer
statistics. CA Cancer J Clin. 2011;61(6):409-18.
American Cancer Society. Breast cancer facts and figures
Atlanta: ACS; 2016.
Ahmed RL, Thomas W, Yee D, Schmitz KH. Randomized
controlled trial of weight training and lymphedema in breast
cancer survivors. J Clin Oncol. 2006;24(18):2765-72.
World Health Organization. BMI classification [acesso em 4
jul. 2013]. Disponível em: http://bit.ly/KuIJLK
Buchholz TA, Avritscher R, Yu TK. Identifying the “sentinel
lymph nodes” for arm drainage as a strategy for minimizing
the lymphedema risk after breast cancer therapy. Breast
Cancer Res Treat. 2009;116(3):539-41.
Camargo MC, Marx AG. Reabilitação física no câncer de
mama. São Paulo: ROCA; 2000.
Demark-Wahnefried W, Campbell LK, Hayes SC. Weight
management and its role in breast cancer rehabilitation.
Cancer. 2012;118(80):1-26.
Garther R, Jensen MB, Kronborg L, Ewertz M, Kehlet H,
Kroman N. Self-reported arm-lymphedema and functional
impairment after breast cancer treatment: a nationwide
study of prevalence and association factors. Breast J.
;19(6):506-15.
Helyer LK, Varnic M, Le LW, McCready D. Obesity is a risk
factor for developing postoperative lymphedema in breast
cancer patients. Breast J. 2012;16(1):48-54.
Banin Hirata BK, Oda JMM, Losi Guembarovski R, Ariza CB,
de Oliveira CEC, Watanabe MAE. Molecular markers for
breast cancer: prediction on tumor behavior. Dis Markers.
; 2014(513158):1-12.
Lee HD, Ahn SG, Lee AS, Lee HM, Jeong J. Prospective
evaluation of the feasibility of sentinel lymph node biopsy
in breast cancer patients with negative axillary conversion
after neoadjuvant chemotherapy. Cancer Res Treat.
;47(1):26-33.
Honnor A. Classification, aetiology and nursing management
of lymphoedema. Br J Nurs. 2008;17(9):576-86.
Kwan ML, Darbinian J, Schmitz KH, Citron R, Partee P, Kutner
SE, Kushi LH. Risk factors for lymphedema in a prospective
breast cancer survivorship study: the pathways study. Arch
Surg. 2010;145(11):1055-63.
Mahamaneerat WK, Chi-Ren S, Stewart BR, Armer JM. Breast
cancer treatment, BMI, post-op swelling/lymphodema. J
Lymphoedema. 2008;3(2):38-44.
Martín, ML, Hernãndez MA, Avendaño C, Rodríguez F,
Martínez H. Manual lymphatic drainage therapy in patients
with breast cancer related lymphedema. BMC Cancer.
;11(94):1471-76.
Meeske KA, Sulliva-Halley J, Smith AW, McTiernan A,
Baemgartner KB, Harlan LC, et al. Risk factors for arm
lymphedema following breast cancer diagnosis in Black
women and White women. Breast Cancer Res Treat.
;113(2):383-91.
Mansel RE, Fallowfield L, Kissin M, Goyal A, Newcombe
RG, Dixon JM, et al. Randomized multicenter trial sentinel
lymph node biopsy versus standard axillary treatment in
operable breast cancer: the almanac trial. J Natl Cancer Inst.
;98(9):599-609.
Pereira AC, Freitas-Júnior R, Martins KA, Pereira AC,
Pereira CE, Martins E. Alterações venosas e linfáticas em
mulheres com linfedema após linfadenectomia axilar no
tratamento do câncer de mama. Rev Bras Ginecol Obstet.
;35(4):171-7.
Pérez-Hernández AI, Catalán V, Gómez-Ambrosi J,
Rodríguez A, Frunbeck G. et al. Mechanisms linking excess
adiposity and carcinogenesis promotion. Front Endocrinol.
;5(65):1-17.
Petrek JÁ, Heelan MC. Incidence of breast carcinoma-related
lymphedema. Cancer. 1998;83(15):2776-81.
Paskett ED, Dean JÁ, Oliveri JM, Harrosp P. Cancer-related
lymphedema risk factors, diagnosis, treatment, and impact:
a review. J Clin Oncol. 2012;30(30):3726-33.
Rezende LF, Pedras FV, Ramos CD, Gurgel, MSC. Avaliação
das compensações linfáticas no pós-operatório de câncer
de mama com dissecção axilar através da linfocintilografia.
J Vasc Bras. 2008;7(4):370-5.
Ridner SH, Diefrich MS, Stewart BR, Armer JM. Body mass
index and breast cancer treatment-related lymphedema.
Support Care Cancer. 2011;19(6):853-7.
Shaw C, Mortimer P, Judd PA. A randomized controlled trial
of weight reduction as a treatment for breast cancer-related
lymphedema. Cancer. 2007;110(8):1868-74.
Thomson CA, Thompson PA, Wright-Bea J, Nardi E,
Frey GR, Stopeck A. Metabolic syndrome and elevated
C-reactive protein in breast cancer survivors on
adjuvant hormone therapy. J Womens Health (Larcmt).
;18(12):2041-7.
Ahmed RL, Schmitz KH, Prizment AE, Folsom AR. Risk
factors for lymphedema in breast cancer survivors, the
low a women’s health study. Breast Cancer Res Treat.
;130(3):981-91.
Shih YC, Xu Y, Cormier JN, Giordano S, Ridner SH, Buchholz
TA, et al. Incidence, treatment costs, and complications
of lymphedema after breast cancer among women of
working age: a 2-year follow-up study. J Clin Oncol.
;27(12):2001-14.
Ugur S, Arıcı C, Yaprak M, Mescı A, Arıcı GA, Dolay K, et al.
Risk Factors of breast cancer-related lymphedema. Lymphat
Res Biol. 2013;11(2):72-5.
Zhu YQ, Xiu YH, Liu FH, Guo Q, Shen PP, Tian Y. Systemic
analysis on risk factors breast cancer related lymphedema.
Asian Pac J Cancer Prev. 2014;15(6):6535-41.
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