Pulp tissue from primary teeth: new source of stem cells

Authors

  • Paloma Dias Telles Federal University of Bahia; Dental School; Department of Community Dentistry and Pediatric Dentistry
  • Maria Aparecida de Andrade Moreira Machado University of São Paulo; Bauru School of Dentistry; Department of Pediatric Dentistry, Orthodontics and Community Health
  • Vivien Thiemy Sakai Federal University of Alfenas; Dental School
  • Jacques Eduardo Nör University of Michigan; School of Medicine; Department of Otolaryngology

DOI:

https://doi.org/10.1590/S1678-77572011000300002

Keywords:

Tissue regeneration, Dental pulp, Tissue engineering, endodontics

Abstract

SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin.

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Published

2011-06-01

Issue

Vol. 19 No. 3 (2011)

Section

Original Articles

License

Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.

 

 

How to Cite

Telles, P. D., Machado, M. A. de A. M., Sakai, V. T., & Nör, J. E. (2011). Pulp tissue from primary teeth: new source of stem cells . Journal of Applied Oral Science, 19(3), 189-194. https://doi.org/10.1590/S1678-77572011000300002