Osteoradionecrosis of the jaws: case series treated with adjuvant low-level laser therapy and antimicrobial photodynamic therapy

Autores

  • Guilherme Henrique Ribeiro Universidade Federal de Santa Catarina, Núcleo de Odontologia Hospitalar do Hospital Universitário, Florianópolis, SC
  • Mariana Comparotto Minamisako Serviço de Odontologia do Centro de Pesquisas Oncológicas de Santa Catarina, Florianópolis, SC
  • Inês Beatriz da Silva Rath Universidade Federal de Santa Catarina, Núcleo de Odontologia Hospitalar do Hospital Universitário, Florianópolis, SC
  • Alyne Simões Universidade de São Paulo, Departamento de Biomateriais e Biologia Oral, São Paulo, SP
  • Keila Cristina Rausch Pereira Universidade do Sul de Santa Catarina, Departamento de Odontologia, Palhoça, SC
  • Liliane Janete Grando Universidade Federal de Santa Catarina, Núcleo de Odontologia Hospitalar do Hospital Universitário, Florianópolis, SC https://orcid.org/0000-0002-6876-1151

DOI:

https://doi.org/10.1590/1678-7757-2017-0172

Palavras-chave:

Osteoradionecrosis, Oral cancer, Radiotherapy, Low-level laser therapy, Antimicrobial photodynamic therapy

Resumo

Background: Osteoradionecrosis of the jaw (ORNJ) is the most severe and complex sequel of head and neck radiotherapy (RT) because of the bone involved, it may cause pain, paresthesia, foul odor, fistulae with suppuration, need for extra oral communication and pathological fracture. We treated twenty lesions of ORNJ using low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT). The objective of this study was to stimulate the affected area to homeostasis and to promote the healing of the oral mucosa. Methods: We performed aPDT on the exposed bone, while LLLT was performed around the bone exposure (red spectrum) and on the affected jaw (infrared spectrum). Monitoring and clinical intervention occurred weekly or biweekly for 2 years. Results: 100% of the sample presented clinical improvement, and 80% presented complete covering of the bone exposure by intact oral mucosa. Conclusion:
LLLT and aPDT showed positive results as an adjuvant therapy to treat ORNJ.

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Publicado

2022-08-31 — Atualizado em 2022-08-31

Versões

Edição

v. 26 (2018)

Seção

Artigos Originais

Licença

Copyright (c) 2022 Journal of Applied Oral Science

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.

 

 

Como Citar

Osteoradionecrosis of the jaws: case series treated with adjuvant low-level laser therapy and antimicrobial photodynamic therapy. (2022). Journal of Applied Oral Science, 26, e20170172. https://doi.org/10.1590/1678-7757-2017-0172